C&T Round Up for Dec & Jan!

Issue 161 | January 28, 2022
4 min read
Capsid and Tail

This week, we highlight the features we published in Dec & Jan! Learn about combining phages with antibiotics, scaling up phage production, the new Web3 x science movement, and catch Phage Directory’s 2021 reflection and 2022 outlook!

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Submit your manuscript here for the March issue of PHAGE Journal!

Check out the top 2 downloaded articles from December’s Special Issue on Phage Informatics and AI:

  • From Trees to Clouds: PhageClouds for Fast Comparison of 640,000 Phage Genomic Sequences and Host-Centric Visualization Using Genomic Network Graphs — Guillermo Rangel-Pineros et al.

  • Phage Annotation Guide: Guidelines for Assembly and High-Quality Annotation — Dann Turner et al.

Urgent January 27, 2022

Urgent need for Klebsiella variicola phages for a patient in Germany

Phage Therapy

We are urgently seeking Klebsiella variicola phages for a patient in Germany

Ways to help at this stage:

  • By sending your phages for testing on the patient’s strain
  • By receiving the strain and testing your phages
  • By receiving the strain and using it to search for new phages against the organism
  • By offering to prepare phages supplied by others to clinical grade
  • By helping spread the word about this request
  • By providing us with names/email addresses of labs you think we should contact

Please email [email protected] if you can help in any way, or if you would like further details/clarification.

Let’s make a difference,
Phage Directory

What’s New

Clinical trial approval: Pherecydes Pharma obtains ANSM Approval for its PhagoDAIR program, which treats osteoarticular infections of prosthetic joints caused by Staphylococcus aureus.

Clinical TrialPhage Therapy

ACD Pharma is constructing a large-scale phage production plant.

Biotech newsPhage productionPharma

Paper: Staphylococcal phages adapt to new hosts by extensive attachment site variability — Helena Leinweber et al.

Phage attachmentResearch paper

Paper: A new sugar for an old phage: a c-di-GMP-dependent polysaccharide pathway sensitizes Escherichia coli for bacteriophage infection — Benjamin Sellner et al.

Phage biologyResearch paper

Paper: Isolation and characterization of Campylobacter jejuni–specific bacteriophages from Germany and their suitability for use in food production — Severin Michael Steffan et al.

Phage in agriculturePhage in foodResearch paper

Latest Jobs

Phage engineeringPost Doc
Postdoc in phage engineering: The Hartmann lab at Northwestern University is seeking independent, resourceful postdoc researchers experienced in molecular biology & interested in microbial ecology and infectious disease. Potential projects include development of ecologically inspired molecular therapeutics for infection. Candidates also encouraged to propose research topics of their own related to environmental chemistry, microbiomes.
Engineered phagesPost Doc
Postdoc: Join the Talbert Research Group at Iowa State University to work on an NIH-funded project focused on bacteriophage engineering for therapeutic applications.
BioinformaticsPhage TherapyPost Doc
Postdoc: CSIRO Postdoctoral Fellowship in Phage Therapy Bioinformatics, to develop new technology for phage therapy, in conjunction with the MRFF Frontiers funded Phage Australia project.
MetagenomicsPhD projectVirus-host Interactions
PhD candidate to characterize host-virus mechanisms, investigate the evolutionary processes that led to their emergence, and measure their activity in diverse biomes.

Community Board

Anyone can post a message to the phage community — and it could be anything from collaboration requests, post-doc searches, sequencing help — just ask!

Thanks to all who came out to the first iVoM Season 2 event of 2022!

Next: Feb 2 from 2-3 PM CET
Topic: Phage application in the One Health approach.
Speakers: Dr. Cath Rees, Prof. Mariana Piuri, Prof. Lone Brøndsted.

If you want to join this series, which will run through May, please register at https://ivom.phage.directory — as many of you know, ISVM is asking for a small contribution from senior scientists and industry for access to this series, which will support ISVM’s activities now and in the future.

Phage Directory is a proud partner of this event, and so are the local organizers for VoM 2022, the upcoming in-person/hybrid conference in Portugal July 18-22!

ISVMPhage DirectoryVirtual EventViruses of microbesiVoM

Hi, I’m looking for a Staph aureus phage that is either phage K or a close relative. I want to use this in my animal model of diabetic foot ulcer infection. I’m at Flinders University in Australia. Thanks. Peter Speck ([email protected])

Diabetic foot ulcersSeeking phage for research

Welcome new Instill members this month! David Adams, Nouri Ben Zakour, Leon Steiner, Kafayath Fabiyi, David Adams, Yédia Franshesca Djohoun, Danielle Peters, Vijay Singh Gondil.

Want to give and get help from your fellow phage community members with their experiments and manuscripts?

Join Instill and see if you can help!

Instill Science

C&T Round Up for Dec & Jan!

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Postdoctoral Researcher
Iredell Lab, The Westmead Institute for Medical Research, Sydney, Australia, Phage Australia

Stephanie is a postdoctoral researcher for the Iredell Group at Westmead Institute for Medical Research, NSW. Her project focuses on phage therapy for compassionate human cases (as part of Phage Australia), with a particular interest in Staphylococcal phages. In 2021, Stephanie completed her thesis titled ‘Exploring phage therapy for Staphylococcus pseudintermedius infections in canines’. Steph is always willing to chat about phage research and would like to connect with phage biotech companies.

In this month’s Capsid & Tail Monthly Round Up issue, we’re highlighting the five feature articles we published in December and January (a two-for-one special!). Be sure to check them out if you missed them, and let us know if you have thoughts, comments or questions! Reach us anytime by email or Slack!

C&T Throwback!

There’s lots of great phage stuff in the C&T archive! Check out this article on Patient perspective: My life since learning of phage therapy one year ago by Ella Balasa, a cystic fibrosis patient who received phage therapy from Yale researchers in 2019.

Many thanks to Atif Khan and Stephanie Lynch for finding and summarizing this week’s phage news, jobs and community posts!

Capsid & Tail

Follow Capsid & Tail, the periodical that reports the latest news from the phage therapy and research community.

We send Phage Alerts to the community when doctors require phages to treat their patient’s infections. If you need phages, please email us.

In collaboration with

Mary Ann Liebert PHAGE

Supported by

Leona M. and Harry B. Helmsley Charitable Trust

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