C&T Round Up for November 2021

Issue 155 | December 3, 2021
7 min read
Capsid and Tail

This week, we highlight the feature articles we published in November! Learn about optimizing the route for phage delivery, single use bioreactor technologies vs. traditional solutions, and phage therapy to combat a shell infection in a sea turtle!

Sponsor

Cellexus 4L bags

4L bioreactor bags are now available for the CellMaker bioreactor system. With working volumes from 1.5L to 4L, users can produce phage at the quantities required, in the controlled environment they need.

Find out more about Cellexus’ new bags here!

What’s New

JPIAMR (Joint Programming Initiative on Antimicrobial Resistance) has awarded funding to multiple new phage-related projects in the One Health space! Funded phage projects include:

  • Use of phage applications to combat MRSA at the sow-piglet interface to reduce exposure of staff and contamination of the environment (PHAGE-EX);
  • Phage treatment and wetland technology as intervention strategy to prevent dissemination of antibiotic resistance in surface waters (PhageLand);
  • Phage therapy to reduce AMR Enterobacteria spread from a One Health perspective (Phage-Stop-AMR)!

Congratulations to all the awardees!

Grant funding newsOne Health
Phage-host interactionsResearch paper

Community Board

Anyone can post a message to the phage community — and it could be anything from collaboration requests, post-doc searches, sequencing help — just ask!

Join us next week for the last PHAVES event of the year (#25!). There will be phages AND puppies!

Dr. Stephanie Lynch of La Trobe University will share her recently completed PhD research on phage therapy for treating Staphylococcus pseudintermedius infections in canines!

When: Tues, Dec 7 at 4PM EST // 8AM Dec 8 AEDT (Sydney, Australia).

Register at https://phaves.phage.directory/schedule/phaves-25!

PHAVESVirtual Event

phageSuisse is hosting a webinar on December 7th on “Evaluation of phage therapy for the treatment of Staphylococcus aureus endovascular infections” by Jonathan Save PhD Student – University of Lausanne, Switzerland. Register here.

Phage TherapyVirtual Event

Many of us are excited for the upcoming Viruses of Microbes (VoM) conference finally taking place summer 2022 in Portugal (after being rescheduled from 2020). In collaboration, the International Society for Viruses of Microorganisms (ISVM), Phage Directory, and the organizers of VoM 2022 are excited to announce Season 2 of iVoM, a series of online lectures from prominent researchers studying viruses of microbes. Seven sessions will run from December 2021 to May 2022, in the lead-up to the exciting in-person version of VoM, July 2022.

The first iVoM2 event will be Dec. 8th at 12:00 PM (noon) CET, under the theme "Control on Viral Action: regulation of viral activity by other viruses and mobile genetic elements".

It will feature talks by:

  • Dr. Aude Bernheim, INSERM, France: “Systematic and quantitative view of the antiviral arsenal of prokaryotes”
  • Prof. Martin Polz, Univ. of Vienna, Austria: “The dynamics of bacterial innate defenses against phage”
  • Dr. Matthias Fischer, MPI for Medical Research, Germany: “The sleeper within - how endogenous virophages may defend protists against giant viruses”

Chair:

  • Prof. Corina Brussaard (Royal Netherlands Institute for Sea Research, Netherlands)
  • Dr. Alex Petrovic Fabijan (Westmead Institue for Medical Research and University of Sydney, Australia)

Register at https://ivom.phage.directory!

The rest of iVoM Season 2 will take place in 2022 and consist of six additional sessions (#2-7) on the topics of:

  1. Raiders of the third domain
  2. Phage application in the One Health approach
  3. Endless virus diversity most beautiful
  4. Environmental impact of virus-host interactions
  5. Models for viral action
  6. Personalised phage therapy
Virtual EventISVMPhage Directory

Phage Directory’s new structured peer feedback platform, Instill Science, is now live, and the first few requests have been posted and replied to!

Can you help your fellow phage researchers by providing a second set of eyes on their work? If so, check out the active requests. Currently, Marwan M. Saleh, Bharat Jhunjhunwala, Steve Abedon, Stephen Amankwah, Noutin Fernand Michodigni and Jan Zheng are looking for feedback or collaborators, ranging from feedback on a study on phage therapy and a phage book chapter, to help with experiments and tools, to those willing to have a conversation about phage databases.

Become an Instill member!

What does feedback look like? Spend 30 mins reading through and giving your first impressions and overarching thoughts on any given piece of work. Your contributions will be tracked and recognized, and you’ll be helping fellow researchers by sharing your expertise.

Thanks so much to those who have already responded to these requests and are working to provide feedback already: Betty Kutter, Urmi Bajpai, Tobi Nagel, Daniel Schwartz, Katharine Muscat, and Atif Khan! You are all amazing and we are so grateful for your support!

Submit your own request for help!

Instill SciencePhage DirectorySeeking collaborator

Thank you to everyone that joined us for our November PHAVES, which was a seminar by Prof. Julianne Grose (phage researcher) and Dr. Whitney Greene, DVM (veterinarian) talking about phage therapy for a sea turtle — watch the recording here! If you miss any of the PHAVES events you can always watch the recordings on the Phage Directory YouTube.

PHAVESPhage Therapy

C&T Round Up for November 2021

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Phage microbiologist and co-founder of Phage Directory
Co-founder
Phage Directory, Atlanta, GA, United States

Jessica Sacher is a co-founder of Phage Directory and has a Ph.D in Microbiology and Biotechnology from the University of Alberta.

For Phage Directory, she takes care of the science, writing, communications, and business aspects.

In this month’s Capsid & Tail Monthly Round Up issue, we’re highlighting the four feature articles we published in November. Be sure to check them out if you missed them, and let us know if you have thoughts, comments or questions! Reach us anytime by email or Slack!

C&T Throwback!

There’s lots of great phage stuff in the C&T archive! Check out “Looking back on iVoM: Six webinars covering all aspects of viruses of microbes”, by Ivone Martins and Luís Melo, co-organizers of iVoM Season #1. (Catch yourself up just in time for iVoM Season #2, which starts next week!)


Many thanks to Atif Khan for finding and summarizing this week’s phage news, jobs and community posts, and to Lizzie Richardson and Stephanie Lynch for help editing!

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