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This month we heard about how Sartorius' columns can bring down endotoxins close to zero. There's also a new phage data resource called Phage Base! Lastly, we also picked a couple of super interesting papers this month — one about how antib

🎙️ New Podovirus Podcast Episode Alert! I had such a great time talking to Jesus Fernandez-Rodriguez, PhD, VP of Technology at Eligo Bioscience, about how they're editing live microbes in the mouse gut with engineered phages! 🧬 Highligh

The second UN General Assembly High-Level Meeting on Antimicrobial Resistance  convened yesterday to address the urgent global health crisis of AMR and its implications for public health, particularly in low- and middle-income countries.

A 75-year-old female patient with recurrent Pseudomonas septicaemia and arterial stents was treated using a phage–meropenem combination therapy at Tampere University Hospital, Finland. A 3-phage P. aeruginosa cocktail was given IV together

For OMKO1 and LPS-5, two lytic phages used in Felix Biotech’s CF trial recently, Dea M. Müller and colleagues show that determinants of their host range in P. aeruginosa are bacterial receptors, rather than anti-phage defence mechanisms.

Peiying Ho and colleagues from the Singapore-MIT Alliance for Research and Technology screened the PA14NR transposon mutant library and identified key genes involved in P. aeruginosa phage resistance. They found 78 mutants capable of thrivi

A novel phage, TS33, targeting Hafnia species in a model Brie-like cheese community; many host factors that contribute to infectivity are O-antigen genes.

CNRS, France is hiring a postdoc to study mechanisms of selective phage DNA packaging and bacterial DNA transduction in Bacillus subtilis.

In a recent interview, Dr. Evelien Adriaenssens (Quadram Institute) discusses her career journey to becoming a Group Leader, focusing on the role of phages in the gut microbiome to promote health and combat disease. She reflects on the dive

David Harper discusses the complexities and limitations of using phages as therapeutics in his recent LinkedIn post, emphasizing the challenges posed by the immune system and the size of phages compared to conventional antibiotics.

How do we remove impurities from our phage preparations, and get our endotoxins down close to zero? This week we've got Ažbe Žnidaršič and Lucija Rebula from Sartorius BIA Separations here to tell us about how CIMmultus monolith chromatogra

Dr. Andrea Fossati at the Karolinski Institute is seeking a postdoctoral researcher in phage biology and antimicrobial resistance to work on phage defense systems.

CIMmultus monolithic columns offer an efficient solution for phage purification, ensuring high recovery rates and fast processing to meet the demands of phage-based therapies. Sartorius BIA Separations' Cornerstone team is available to help

🎙️ New Podovirus Podcast Episode Alert! I had such a great time talking to Jesus Fernandez-Rodriguez, PhD, VP of Technology at Eligo Bioscience, about how they're editing live microbes in the mouse gut with engineered phages! 🧬 Highligh

PhageEU is urging phage researchers to join their mission to raise awareness about the potential applications of phages and influence regulatory environments in the EU, especially with new parliamentary appointments on the horizon PhageEU m

Kurzgesagt released a new video on viromes and their impact on health, emphasizing the role of phages in microbiome dynamics! Check it out!

The BASEL collection of E. coli phages has been expanded — 36 new ones have been added! These phages were deeply characterized genomically and phenotypically, from receptors to antiviral defense sensitivity to host range. Looking at the res

Plasmid-dependent phages used to be used in phage typing, but haven’t survived the genomics era — there are no records of them in phage banks, and it’s been unclear if they can ever be recovered. However, a new wave of studies reporting the

A phage cocktail targeting Yersinia pestis provided ~88% post-exposure protection in a rat model of pneumonic plague!

Here’s a handy comparison of expression systems for phage lysin production, with key considerations for host selection and evaluating recent literature.