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  1. Therapy studies

    Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®

    Status unconfirmed. Checked 2026-10-03. DUOFAG® is a phage cocktail containing bacteriophages active against Staphylococcus aureus and Pseudomonas aeruginosa. It is an investigational medicinal product for the treatment of surgical site inf

    Phage TherapyStaphylococcus aureusPseudomonas aeruginosaSurgical site infectionBacteriophageBacterial infections
  2. Therapy studies

    Establishing Personalized Phage Therapy and Its Comparative Cost in Difficult-to-treat Infections (EPHICACI)

    Recruiting. Checked 2026-10-03. EPHICACI is a multicenter, prospective study that continues and expands the monocentric PHAGEFORCE registry initiated at UZ Leuven. In Belgium, phage therapy can be applied as standard-of-care only in patient

    Bacteriophage therapyPersonalized treatmentDifficult-to-treat infectionAntimicrobial resistanceMusculoskeletal infectionsChronic rhinosinusitisPersistent bacteremiaPulmonary infectionsCystic fibrosisBronchiectasisHidradenitis suppurativa
  3. Therapy studies

    Phase 1/2a to Assess the Safety and Tolerability of TP-122A for the Treatment of Ventilator-Associated Pneumonia

    Not authorised. Checked 2026-10-03. Given the challenges of treating complex cases of VAP caused by P. aeruginosa and K. pneumoniae, TechnoPhage developed a bacteriophage cocktail (TP-122) against those pathogens, aiming to provide a hospit

  4. Therapy studies

    Phage Therapy for Recurrent UTIs in Kidney Transplant Recipients

    Recruiting. Checked 2026-10-03. This proposal will take an important first step in the study of phage therapy for treatment of recurrent urinary tract infection (rUTI) in female kidney transplant recipients (KTR); a common condition that is

  5. Therapy studies

    Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection

    Active, not recruiting. Individual-case protocol. Checked 2026-10-03. This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage cocktail to treat and prevent the recurrence of a methicillin-s

    Single patientBacteriophagePhage
  6. Therapy studies

    Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria

    Recruiting. Checked 2026-10-03. This is a Phase 1b study to assess the safety, tolerability, PK, and PD of investigational phage therapy (IP) in adults with SCI and bladder colonization (ASB). It is a single-center, randomized, double-blind

    BacteriophageBacteriuriaPhage TherapySpinal Cord InjuryIntravesicular infusionNeurogenic BladderIntermittent catheterizationRandomized clinical trial
  7. Therapy studies

    Proof of Concept Study to Assess Safety and Efficacy of Phage Therapy in Hip or Knee Prosthetic Joint Infections Due to Staphylococcus Aureus Treated by DAIR.

    Not yet recruiting. Checked 2026-10-03. Total joint replacements are effective for chronic pain but can lead to Prosthetic Joint Infections (PJI), primarily caused by Staphylococcus aureus and resistant to antibiotics. Standard treatment in

    Prosthetic Joint InfectionPJIBacteriophagesPhagesDAIRPhage TherapyAntimicrobials
  8. Therapy studies

    Safety and Tolerability of NTR-101 in Patients With Acute Alcohol-Associated Hepatitis

    Not yet recruiting. Checked 2026-10-03. The goal of this clinical trial is to learn about the safety and tolerability of NTR-101 in adult participants suffering from acute alcohol-associated hepatitis (AH). The drug is intended for use in

    bacteriophagesalcohol-associated hepatitisNTR-101bacteriophage therapy
  9. Therapy studies

    Bacteriophage Clinical Trial for Periprosthetic Joint Infection of Multidrug Resistant Pseudomonas Aeruginosa

    Expanded access. Individual-case protocol. Checked 2026-10-03. This is a single patient study (SPS) that aims to test the bacteriophage treatment as an experimental treatment on a patient suffering from chronic periprosthetic joint infectio

    Phage therapyPeriprosthetic Joint InfectionBacteriophage
  10. Therapy studies

    Bacteriophage Therapy for Morganella Morganii Prosthetic Joint Infection

    Active, not recruiting. Individual-case protocol. Checked 2026-10-03. This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Morganell

    BacteriophagePeriprosthetic joint infectionPhage therapy
  11. Therapy studies

    Use of Phage Therapy for Treatment of a Periprosthetic Joint Infection

    Active, not recruiting. Individual-case protocol. Checked 2026-10-03. The goal of this clinical trial is to learn about the safety, tolerability and activity or efficacy of systemic intravenous and intraarticular administration of a mono-ba

  12. Therapy studies

    Bacteriophages in Addition to Antibiotics for the Treatment of Patients With Infective Endocarditis

    Recruiting. Checked 2026-10-03. Infective endocarditis (IE) is an endocardial lesion caused by bacterial and/or fungal infection that most commonly affects the heart valves and/or the endocardium around implanted intracardiac devices. In ge

    infective endocarditisbacteriophages
  13. Therapy studies

    Natural Product System and Lifestyle Modification

    Completed. Checked 2026-10-03. The goal of this clinical trial is to learn whether four dietary supplements and lifestyle changes can affect gene expression and blood markers in healthy volunteers. The main questions it aims to answer are:

    Gene expressionEssential oilCopaibaOmega 3ProbioticGreens powder
  14. Therapy studies

    Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

    Recruiting. Checked 2026-10-03. This is a Phase 1b/2a study in allogenic hematopoietic stem cell transplant patients to investigate the safety, PK, PD and preliminary efficacy of multiple oral administrations of SNIPR001 when given concomit

  15. Therapy studies

    Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection

    Not yet recruiting. Individual-case protocol. Checked 2026-10-03. This purpose of this clinical trial is to evaluate the safety, tolerability and efficacy of a bacteriophage therapy in a patient with a methicillin-susceptible Enterococcus f

  16. Therapy studies

    Study With Phage for CF Subjects With Pseudomonas Lung Infection

    Conflicting status. Checked 2026-10-03. The goal of this Phase 2b clinical trial is to see if nebulized phage (BX004) can treat chronic Pseudomonas aeruginosa (PsA) lung infection in CF subjects. The primary goal is to see if 8 weeks of twi

  17. Therapy studies

    Biomarkers of Phage Treatment Response in NTM and Other Infections

    Recruiting. Checked 2026-10-03. This study aims to identify biomarkers associated with response to phage therapy for refractory bacterial infections. This includes mycobacteriophage treatment for patients with nontuberculous mycobacterial i

    Bacteriophage therapyRefractory bacterial infection
  18. Therapy studies

    Bacteriophage Cocktail Therapy for Multidrug-Resistant Gram-Negative Ventilator-Associated Pneumonia

    Not yet recruiting. Checked 2026-10-03. The purpose of this study is to systematically evaluate the efficacy and safety of bacteriophage cocktail therapy in patients with ventilator-associated pneumonia caused by Gram-negative bacterial inf

    phage therapyventilator-associated pneumoniaphage cocktail
  19. Therapy studies

    Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary Infection

    Invitation only. Individual-case protocol. Checked 2026-10-03. This study aims to use mycobacteriophage therapy, using identified in-vitro effective Mycobacteriophage Muddy_HRMN0052, along with combination conventional antimycobacterial the

    non-tuberculous mycobacteriabacteriophagemycobacteriophagemycobacterium abscessuspulmonary disease
  20. Therapy studies

    Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection

    Recruiting. Checked 2026-10-03. The goal of this clinical trial is to learn if a new treatment called AchromoPhage is safe and well tolerated in adults with cystic fibrosis (CF) who have long-term lung infections caused by Achromobacter bac

    Bacteriophage TherapyPhage TherapyAchromoPhageMultidrug-Resistant InfectionsLung InfectionPulmonary Infectioncystic fibrosisAchromobacter
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