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8,013 results

  1. Therapy studies

    Safety of Combined Intravenous Antibiotic and Bacteriophage Therapy in Adults With Cystic Fibrosis and Antibiotic-Resistant Lung Infections

    Not yet recruiting. Checked 2026-10-03. This is a Phase 1, open-label, multi-center pilot study evaluating the safety and microbiological activity of intravenous (IV) bacteriophage therapy in combination with standard IV antibiotics in adul

    cystic fibrosisCFPhagebacteriophage
  2. Therapy studies

    A Randomized Controlled Trial (RCT) of Yiqi Huoxue Jiedu Formula Combined With Bacteriophages in the Treatment of Severe Pneumonia Caused by Drug-resistant Gram-negative Bacilli

    Not yet recruiting. Checked 2026-10-03. Through a prospective randomized controlled trial, we systematically evaluate the effects of Yiqi Huoxue Jiedu Formula combined with bacteriophage therapy on the bacterial clearance rate, disease impr

  3. Therapy studies

    Evaluation of Safety and Efficacy of Phage Therapy for Drug-resistant Bacterial Infections: An Exploratory, Prospective Single-arm Study

    Not yet recruiting. Checked 2026-10-03. This study is an investigator-initiated, single-center, exploratory clinical trial designed to evaluate the safety and efficacy of phage therapy in patients with urinary tract infections caused by dru

    Phage TherapyDrug-resistant bacteriaUrinary tract infectionPersonalized phage cocktail
  4. Therapy studies

    Bacteriophage for Chronic Multidrug-Resistant Mycobacterium Abscessus Subsp. Abscessus Pulmonary Infection

    Not yet recruiting. Individual-case protocol. Checked 2026-10-03. The objective of this study is to evaluate mycobacteriophage therapy using in-vitro validated mycobacteriophage DP-QB-MYA-002 in combination with conventional antimycobacteri

  5. Therapy studies

    Bacteriophage Therapy for Staphylococcus Lugdunensis Prosthetic Joint Infection

    Not yet recruiting. Individual-case protocol. Checked 2026-10-03. This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Staphylococcu

    BacteriophagePeriprosthetic joint infectionPhage therapy
  6. Therapy studies

    MP101 in Adults With Acute Pseudomonas Aeruginosa Pneumonia

    Recruiting. Checked 2026-10-03. The purpose of this study is to evaluate the safety and tolerability of a single intravenous dose of MP101 administered in addition to standard antibiotic therapy in adult patients with acute Pseudomonas aeru

    Acute Pseudomonas Aeruginosa Pneumonia
  7. Therapy studies

    Bacteriophage Therapy for Orthopedic Implant-Associated Infections

    Not yet recruiting. Checked 2026-10-03. A Prospective, Single-Center, Single-Arm Clinical Study with a Pre-Post Self-Controlled Design Evaluating the Efficacy and Safety of Bacteriophage Therapy for Refractory Orthopedic Implant-Associated

    Bacteriophage TherapyOrthopedic Implant-Associated Infections
  8. Therapy studies

    Yiqi Huoxue Jiedu Formula Combined With Bacteriophages in the Treatment of Severe Pneumonia

    Not yet recruiting. Checked 2026-10-03. Through a prospective randomized controlled trial, we systematically evaluate the effects of Yiqi Huoxue Jiedu Formula combined with bacteriophage therapy on the bacterial clearance rate, disease impr

    bacteriophageYiqi Huoxue Jiedu Formuladrug-resistant bacteriaPneumonia
  9. Therapy studies

    Randomized Controlled Study on the Safety and Efficacy of Phage Cocktail in the Treatment of Multidrug-Resistant Bacterial Skin Infections

    Invitation only. Checked 2026-10-03. This study addresses the increasingly severe global public health challenge of antibiotic resistance, focusing on exploring phage therapy as a potential treatment strategy for multidrug-resistant bacteri

  10. Therapy studies

    "Debridement PhagE AnTibiotics for PJI"

    Not yet recruiting. Checked 2026-10-03. Total joint replacement (TJR) has revolutionized care provided for patients suffering from disabling joint pain. Unfortunately, periprosthetic joint infection (PJI) remains a devastating complication

    Phage therapyPeriprosthetic Joint InfectionBacteriophage
  11. Therapy studies

    A Double-Blind, Placebo-Controlled Study of Nebulized Bacteriophages in Patients With Ventilator-Associated Pneumonia Due to Pseudomonas Aeruginosa

    Not yet recruiting. Checked 2026-10-03. Ventilator-associated pneumonia (VAP) complicates the hospital course of up to 40% of mechanically ventilated patients and is associated with mortality rates approaching 30%, despite appropriate antib

    Nebulized BacteriophagesVentilator Associated Bacterial Pneumonia
  12. Therapy studies

    Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience

    Recruiting. Checked 2026-10-03. Bacteriophages are viruses that can selectively infect specific species and strains of bacteria. Some bacterial species in the human gut have been negatively associated with gut health and skin health. This s

    Gut HealthSkin HealthBacteriophage
  13. Therapy studies

    KIDNAP / UNIFESP KPC decolonization

    Not yet recruiting. Checked 2026-10-03. Bowel decolonization of KPC-producing K. pneumoniae, UNIFESP São Paulo. RBR-9f3whw9

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