Clinical study
PHAGE-MOM-001
Bacteriophage Therapy for Morganella Morganii Prosthetic Joint Infection
| Status | Active, not recruiting |
|---|---|
| Type | Individual-case protocol |
| Countries | Canada |
| Conditions studied | Prosthetic Joint Infections of Hip |
| Study years | 2025–2026 (estimated) |
| Entry review | 2026-10-03 |
Participation
Check the study record or contact the study team for current recruitment and eligibility.
Study eligibility
Inclusion Criteria: * Diagnosis of active chronic prosthetic joint infection * Causative bacteria is susceptible to bacteriophage therapy in vitro * History of multiple failed antibiotic and surgical interventions Exclusion Criteria: * Stage 5 chronic kidney disease * Cirrhosis * A known allergy to phage products * Fever * Involvement in another clinical trial * Pregnancy
Study description
This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Morganella morganii prosthetic joint infection of the hip. The patient has exhausted all conventional therapies, both surgical and medical, at considerable detriment to their quality of life. The treatment involves 2 intra-articular injections of bacteriophages into the joint and surrounding area and 14 days of intravenous phage therapy. The goal is to eliminate the infection and prevent further complications, providing a potential new treatment avenue for patients with difficult-to-treat infections.
Study registrations
| ClinicalTrials.gov | NCT06814756 |
|---|
Recorded study locations (1)
Locations listed in the study record; this does not confirm current recruitment or treatment outside the study. A site label may be older than the overall study status.
Foothills Medical Centre, University of Calgary
Calgary, Canada
Recorded site status: Not separately listed. Study location source ↗
Related programs(1)
University of Calgary / Alberta Health Services phage research
Intake unconfirmed
Recorded program–study link. Website
Notes from the source review
- Single-patient protocol (target/actual n=1); not a broad recruiting program. Planned completion date has passed while registry status remains nonterminal; recheck with site.
Sources and updates
Entry reviewed . This is the date of our source review, not a confirmation of availability today.
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| Study ID | nct06814756 |
|---|