Phase Genomics raised $5.5M from the Bill and Melinda Gates Foundation & NIH to catalog the viruses that infect bacteria. The resulting database could be used to develop new therapeutics & build a surveillance system to detect & respond to microbial threats.
Paper: Identification of phage receptor-binding protein sequences with hidden markov models and an extreme gradient boosting classifier. Twitter thread: ‘AI vs. bioinformatics’ — find out which one won!.
Tool: Pharokka, a dedicated fast phage annotation tool inspired by prokka. Pharokka is designed for users who want one-line, rapid, standarised and scalable phage annotations, much like prokka for prokaryotes.
Paper: Thousands of small, novel genes predicted in global phage genomes.
Blog: Using viruses to treat antibiotic-resistant bacterial infections | National Institutes of Health (NIH).