C&T Round Up for June 2022!

Issue 182 | July 1, 2022
3 min read
Capsid and Tail

This week, we highlight the feature articles we published in June! Learn about what happened when the Phage Australia team shipped a phage around the country, Jean-Paul Pirnay’s views on phage therapy, and how producing phages has changed over the years.

Sponsor

PF EU download report

As we look forward to the 2022 Phage Futures Europe event, 6-7 July in Amsterdam, take a look at the 2021 post-event report, created in collaboration with PhD students from Phage Directory, Sheetal Patpatia and Aël Hardy, to gain insight into phage manufacturing, phage matching and more.

Delve deeper into these conversations at the Phage Futures 2022 event and explore new areas including new clinical data from Eligo Bioscience, Intralytix, PhageLux, improving formulation and manufacturing, computational approaches to phage cocktail design, methods for scaling up, regulatory considerations and more.

Urgent June 23, 2022

Urgent need for Serratia phages for a patient in the USA

Phage Therapy

We are urgently seeking Serratia phages for a patient in the USA

Ways to help at this stage:

  • By sending your phages for testing on the patient’s strain
  • By receiving the strain and testing your phages
  • By receiving the strain and using it to search for new phages against the organism
  • By offering to prepare phages supplied by others to clinical grade
  • By helping spread the word about this request
  • By providing us with names/email addresses of labs you think we should contact

Please email [email protected] if you can help in any way, or if you would like further details/clarification.

Let’s make a difference,
Phage Directory

What’s New

Phase Genomics raised $5.5M from the Bill and Melinda Gates Foundation & NIH to catalog the viruses that infect bacteria. The resulting database could be used to develop new therapeutics & build a surveillance system to detect & respond to microbial threats.

Biotech newsFunding news

Paper: Identification of phage receptor-binding protein sequences with hidden markov models and an extreme gradient boosting classifier. Twitter thread: ‘AI vs. bioinformatics’ — find out which one won!.

AIReceptor binding proteinResearch paper

Tool: Pharokka, a dedicated fast phage annotation tool inspired by prokka. Pharokka is designed for users who want one-line, rapid, standarised and scalable phage annotations, much like prokka for prokaryotes.

Bioinformatics Tool

Paper: Thousands of small, novel genes predicted in global phage genomes.

Phage genomicsResearch paper

Blog: Using viruses to treat antibiotic-resistant bacterial infections | National Institutes of Health (NIH).

NewsPhage Therapy

Latest Jobs

Post Doc
Postdoc at University of Jyväskylä, Finland, with demonstrated experience in microbial/cell cultures, genetic analyses, and/or understanding in phage resistance and CRISPR-Cas adaptation studies in bacteria to join the international research project “Ecology of bacteriophages in mucosa during vertebrate host lifespan”.
Post Doc
Postdoc at University of Nebraska-Lincoln to focus on the development of a live attenuated unmarked vaccine against Johne’s disease. The primary duties and responsibilities are molecular cell biology, molecular genetics, and microbiology approaches (e.g., RT-PCR, plasmid construction, phage propagation, etc.)
Research Support Officer
Research Support Officer: University of Leicester. The Phage Lab Research Group headed by Prof Martha Clokie is seeking a Research Support Officer to help manage human and agricultural phage research projects, and help progress projects through pre-clinical and clinical development.
Post Doc
Postdoc in the laboratory of Prof. Marek Basler at the Biozentrum of University of Basel to unravel novel phenotypes related to type 6 secretion system activity.
Mobile genetic elementsResearch Fellow
Research Fellow in the lab of John Chen at the National University of Singapore, to study the molecular basis of Staphylococcus aureus pathogenesis. Interests of the lab are focused on phages, pathogenicity islands, and other mobile genetic elements.

Community Board

Anyone can post a message to the phage community — and it could be anything from collaboration requests, post-doc searches, sequencing help — just ask!

PhageSuisse is hosting a phage webinar with by Prof. Lars Fieseler from the Institute of Food and Beverage Innovation in Zurich and Wädenswil, Switzerland. He will give a talk about synergy between Erwinia amylovora tailspike protein and phage.

Virtual Event

C&T Round Up for June 2022!

Profile Image
Phage microbiologist and co-founder of Phage Directory
Co-founderPostdoctoral Researcher
Skills

Phage characterization, Phage-host interactions, Phage Therapy, Molecular Biology

I’m a co-founder of Phage Directory and have a Ph.D in Microbiology and Biotechnology from the University of Alberta (I studied Campylobacter phage biology). For Phage Directory, I oversee community building, phage sourcing, communications, science, and our awesome team of volunteers.

As of Feb 2022, I’ve recently joined Jon Iredell’s group in Sydney, Australia as a postdoctoral research scientist for the Phage Australia project. I’m diving back into the lab to help get Phage Australia’s country-wide phage therapy system up and running here, working to streamline workflows for phage sourcing, biobanking and collection of phage/bacteria/patient matching and monitoring data, and integrating it all with Phage Directory’s phage exchange, phage alerts and phage atlas systems.

In this month’s Capsid & Tail Monthly Round Up issue, we’re highlighting the three feature articles we published in June. Be sure to check them out if you missed them, and let us know if you have thoughts, comments or questions! Reach us anytime by email or Slack!

C&T Throwback!

There’s lots of great phage stuff in the C&T archive! Check out this article on PhageUGAL Summer School: Infecting Romanian research with phage by Colin Buttimer, Andrei Sorin Bolocan, Anca Ioana Nicolau, Joan Colom Comas, and Leontina Grigore Gurgu!

Capsid & Tail

Follow Capsid & Tail, the periodical that reports the latest news from the phage therapy and research community.

We send Phage Alerts to the community when doctors require phages to treat their patient’s infections. If you need phages, please email us.

In collaboration with

Mary Ann Liebert PHAGE

Supported by

Leona M. and Harry B. Helmsley Charitable Trust

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