Johanna Sweere and colleagues just published a very exciting paper today in Science! A temperate filamentous phage of Pseudomonas aeruginosa dampens the immune response against P. aeruginosa, which leads to increased P. aeruginosa virulence. (More phage = increased wound severity!) The authors also show that vaccination against this phage works to protect mice against P. aeruginosa. STAT News article | Paper
Announcing a new series of hands-on phage (meta)genomics workshops at this year’s Evergreen International Phage Meeting! Workshops will take place Sat, Aug 3, 4-6 pm and 7-9 pm, and Sun, Aug 4, 9-11 am. An open phage genomics and metagenomics discussion will follow (Sun Aug 4, 11:15 am - 1:30 pm). Workshops will be taught by a group of leaders in the field, including Ramy Aziz, Evelien Adrianssens, Alejandro Reyes and Jason Gill.
Workshops are free with conference registration; extra charge only for Saturday night dorm accomodation if needed. If interested, email firstname.lastname@example.org and specify whether interested in metagenomics issues and/or phage annotation challenges. Spots are limited. It is possible to sign up for Sunday only. More details to come!
The Bacteriophage Biology and Therapeutics Special Interest Group is part of the Australian Society for Microbiology. Their goal is to promote collaborative phage work in and outside Australia, so especially if you do phage work in the area, check them out! They also publish a quarterly blog!
This week, several exciting new papers on the evolution of CRISPR-Cas systems were published. One, by Amelia McKitterick and colleagues from the Seed lab at UC Berkeley, shows how a phage-encoded CRISPR-Cas system interferes with an anti-phage island.
Dr. Krystyna Dabrowska of the Institute of Immunology and Experimental Therapy at the Polish Academy of Sciences has just published a systematic and critical review of the phage pharmacokinetics and bioavailability literature (spanning 1924-2016, including non-English reports).
If you want to better understand US laws affecting the development of prescription drugs, and the roles and responsibilities of the FDA, edX (HarvardX) is running an online course called The FDA and Prescription Drugs: Current Controversies in Context. It’s free to audit the class, which started this week.