About Phage Directory

Our Mission

Interest in phages is ramping up across many sectors, but effective application of phages requires specific expertise.

Our mission is to accelerate the safe and effective use of phages in medicine and industry around the world. We aim to accomplish this goal by curating phage-related content, advising on phage-related topics and coordinating collaborations within and across disciplines.

Background

We are facing a global antibiotic resistance crisis and we need additional or alternative ways to treat patients unable to fight against bacterial infections. Phage therapy is an increasingly viable and scientifically-accepted alternative to antibiotics.

Researchers around the world routinely cultivate phages against most bacterial pathogens faced by patients. However, safely and effectively giving these phages to critically ill patients is challenging — each phage treatment must be customized to each patient’s infection. This process requires a complex collaboration between scientists, doctors, regulatory bodies and families of patients on extremely short notice.

By building and maintaining a free, open-source, public directory of researchers willing and able to provide, test and/or mass-produce phages in response to critically ill patients’ needs, we can connect patients with potentially life-saving cures to otherwise untreatable drug-resistant infections.

Phage Directory is currently an opt-in service, so all labs listed have volunteered to include their labs and phages in the directory. If you’d like to add your lab and phages, please fill out this form: https://phage.directory/join.

— Jess & Jan <>=Σ

Behind the Scenes

This project is a work in a progress. For questions, suggestions, and more, please either email [email protected] or tweet us at @phagedirectory. This directory is currently independently organized and run, with our own time and resources, and is not funded by any organizations.

I first became fascinated with microbes following an inspiring lecture on fecal transplants in mice in 2008, which led me to pursue a PhD in Microbiology and Biotechnology at the University of Alberta in Edmonton, Canada. The major research question I’ve been pursuing since has asked how bacteriophages (or phages, for short) target and kill Campylobacter jejuni, a deadly bacterial pathogen that infects humans around the world.

Along the way, I have realized just how important the answers to questions like these are to getting us closer to solving one of the most important health hurdles humans have faced to date: that of antimicrobial resistance and multidrug-resistant infections.

I’m passionate not only about the idea that phages can be harnessed to treat these infections, but that we are closer than we think to making phage therapy an accessible and promising option for patients.

— Jessica @jessicasacher

Jessica Sacher, PhD
Microbiologist
PhD in Microbiology and Biotechnology, University of Alberta

I completed a PhD in Microbiology and Biotechnology in Christine Szymanski’s lab at the University of Alberta, where I studied the interactions between the gut pathogen Campylobacter jejuni and its bacteriophages.

I am passionate about helping the world utilize phages safely and effectively. I believe collaboration among medical professionals, researchers, companies and regulatory bodies is essential for this to happen, and I hope that Phage Directory can help foster such collaborations.

Jan Zheng
Product Design & Development
Masters in Human-Computer Interaction, CMU

I’m a product designer with a background in computer science, psychology, and a Masters in Human-Computer Interaction from Carnegie Mellon University.

In the past I’ve worked with companies and brands like Verizon Wireless, Cartoon Network, Coca-Cola, Microsoft, L’Oreal, and more to build and design digital products, and to improve product user experiences.