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The Chevallereau group at CNRS, Université de Lyon, France is hiring a postdoc to decipher whether and how prophages mediate resistance against, and coevolve with, virulent phages in P. aeruginosa. For further information: anne.chevallereau

Postdoctoral position: Bacteriophage biology at CNRS in Lyon, France. The project aims at deciphering if and how prophages mediate resistance against, and coevolve with, virulent phages in the opportunistic pathogen Pseudomonas aeruginosa.

The Alfred and Monash University collaboration had explored phage therapy for four patients by February 2024, with patients considered eligible only on compassionate grounds in Australia. The team described the approach as experimental. Alf

Researchers at University Medicine Rostock delivered synthetic mRNA encoding the Cpl-1 phage endolysin into three human cell lines (HEK293T, A549, HepG2), which produced endolysin with activity against Streptococcus pneumoniae. Adding a hum

Integrated resonant photonic crystal cavities in silicon acted as optical nanotweezers that differentiated a single bacterium from a single phage without labeling or surface bioreceptors, and distinguished phages across phenotypically disti

Researchers at the University of Minho and partner institutions show that synthetic M13 phages displaying Aβ-derived peptides bind preferentially to amyloid-β oligomers. In hippocampus tissue from APP/PS1 transgenic mice the phages detected

In this preprint, intravenously administered antipseudomonal phage LPS-5 had blood half-lives of 3.45 and 3.66 hours in wild-type and neutropenic mice, suggesting neutrophil phagocytosis is not a major driver of phage clearance. A gap betwe

Researchers at the Institute of Oceanology, Chinese Academy of Sciences cultured a novel deep-sea cold-seep Planctomycetes strain, ZRK32, which they propose to name Poriferisphaera heterotrophicis. Supplementing nitrate or ammonium induced

A review of in vitro attempts to use bacteriophages and their enzymes, alone or together with antibiotics and other agents, against polymicrobial biofilms, including some therapeutic uses. It also sums up the advantages, disadvantages and p

A Nature Microbiology study from the Universities of Würzburg and Tübingen shows that in Vibrio cholerae the CBASS anti-phage signalling system increases sensitivity to antifolate antibiotics up to tenfold and enables bacterial lysis by the

A Nature Communications study (open access) describes Paride, a newly isolated Pseudomonas aeruginosa phage that can replicate directly in, and lyse, deep-dormant host cells, whereas other phages tested suspended replication until the host

The recombinant endolysin LysAB1245, from phage T1245, showed broad activity against all clinical multidrug-resistant A. baumannii isolates tested across capsular types KL2, 3, 6, 10, 47, 49 and 52, with a reduction of more than 3 log in vi

We are urgently seeking Stenotrophomonas phages for a patient in the USA. Ways to help at this stage: - By sending your phages for testing on the patient's strains - By receiving the patient's strain and testing your phages - By helping s

This week we wrap up 2023 and reflect on our biggest surprises and proudest moments! Things are also changing in 2024... Hey everyone, Welcome to the last issue of 2023! What a whirlwind of a year it’s been – I feel like it was only yeste

Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark is hiring 3 postdocs to unravel novel mechanisms in phage defense and biology using cryo-EM, cryo-ET, and protein bioinformatics/design.

California Institute of Technology is hiring a lab technician to assist with ongoing projects investigating mechanisms and functions of prokaryotic Argonaute proteins.

Phage Phriday on Clubhouse returns for a holiday special on Dec 22, featuring Amanda Burkardt, CEO of new therapeutic phage company Phiogen, and Iddo Weiner, VP of research at BiomX, who recently generated some exciting new phage clinical t

The International Bacteriophage Research Consortium (IBRC) & Open Source Pharma Foundation (OSPF) in association with the Indian Society for Bacteriophage Research and Therapy (SBRT) have started a series of talks by clinicians with experie

Did you know that VoM is heading down under? The Viruses of Microbes (VoM) Conference will take place in Cairns, Queensland, Australia, July 15-19th, 2024. Registration is open now!

Cristina Leal Rodríguez (Copenhagen University Hospital) and colleagues published a new paper on how the infant gut virome is associated with preschool asthma risk independently of bacteria.