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8,013 results

  1. Therapy studies

    Assessing the Efficacy of Anti-staphylococcal Phages in the Management of Infected Foot Ulcers in Diabetes

    Withdrawn. Checked 2026-10-03. Work Package 1: Observational cohort pilot safety study Work Package 2: Randomised, double-blind, placebo controlled pilot study Work Package 3: Observer-blind pilot RCT Assessing the Efficacy of Anti-staphylo

    DiabetesDiabetic Foot DiseaseDiabetic Foot Ulcer
  2. Therapy studies

    Phage Therapy for the Prevention and Treatment of Wound Infections in Burned Patients

    Status unconfirmed. Checked 2026-10-03. The central aim of this trial is to investigate the safety and tolerability of Phage Cocktail-SPK as an adjunct to standard therapy for the prevention and treatment of burns susceptible to infection/o

    BurnsInfectionInfection woundInfection, BacterialInfection Pseudomonas AeruginosaInfection Staphylococcus AureusInfection, Klebsiella pneumoniaeResistant Infection
  3. Therapy studies

    The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia

    Completed. Checked 2026-10-03. Oropharynx is the main source of pathogen microorganisms for the ventilator - associated pneumoniae. As known bacteriophages can eliminate different pathogen microorganisms or reduce a degree of a pathogen's c

  4. Therapy studies

    BacterioPHAGE for Gastrointestinal Health 2 Study

    Completed. Checked 2026-10-03. The BacterioPHAGE for Gastrointestinal Health-2 study is designed to determine if a commercial bacteriophage product can increase the survival and efficacy of probiotic bacteria that will be concurrently admin

    gastrointestinalprobioticbacteriophageBifidobacterium animalis subspecies lactis
  5. Therapy studies

    Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aeruginosa Lung Infections and Cystic Fibrosis

    Completed. Checked 2026-10-03. Phase 1b/2a, double-blind, randomized, placebo-controlled, single and multiple ascending dose study to evaluate the safety, tolerability and phage recovery profile of AP-PA02 multi-bacteriophage therapeutic ca

    phagebacteriophagecystic fibrosisPseudomonasPseudomonas aeruginosa
  6. Therapy studies

    Personalized Phage Treatment in Covid-19 Patients With Bacterial Co-Infections Microbials for Pneumonia or Bacteremia/Septicemia

    Unavailable. Checked 2026-10-03. Phage Treatment in Covid-19 Patients with Bacterial Co-Infections Expanded Access Study of Phage Treatment in Covid-19 Patients on Anti-Microbials for Pneumonia or Bacteremia/Septicemia Due to A. Baumannii,

    Covid19BacteriophagePhageBacteremiaSepticemiaAcinetobacterbaumanniiPseudomonasAeruginosaInfectionStaphAureus
  7. Therapy studies

    Phage Safety Cohort Study

    Recruiting. Checked 2026-10-03. This cohort study aims to describe the adverse events related to the use of bacteriophages to treat serious infections, data from the literature being almost non-existent on this subject. Phage Safety Cohort

    phageadverse eventsevere infectioncompassionate treatment
  8. Therapy studies

    Bacteriophage Therapy in Tonsillitis

    Active, not recruiting. Checked 2026-10-03. The patients received bacteriophage therapy with a liquid piobacteriophage complex (liquid pyobacteriophage complex - PCL). PСL was administered via nebulizer inhalation to irrigate the tonsil muc

    acute tonsillitischildrenbacteriophageimmunityambulatory treatment
  9. Therapy studies

    CYstic Fibrosis bacterioPHage Study at Yale (CYPHY)

    Completed. Checked 2026-10-03. This is a Phase 2 study with primary objective of looking whether YPT-01 phage therapy reduces sputum bacterial load in cystic fibrosis subjects with Pseudomonas aeruginosa. In addition, study evaluates the s

    Pseudomonasbacteriophagephage
  10. Therapy studies

    Phage Safety Retrospective Cohort Study

    Status unconfirmed. Checked 2026-10-03. The aim of this study is to determine the imputability of adverse events in patients who have had phage therapy for the treatment of their bone or joint or implant infection, in order to find out whet

    bone and joint infectionphagotherapyadverse eventProsthetic Joint Infection
  11. Therapy studies

    A Study to Evaluate the Safety, Tolerability, and Fecal Pharmacokinetics of BX002-A in Healthy Adults

    Completed. Checked 2026-10-03. The purpose of study BMX-02-001 is to evaluate the safety, tolerability and feasibility of orally administered BX002-A to deliver viable bacteriophages to the gut. A Phase 1, Randomized, Single-blind, Placebo-

  12. Therapy studies

    Bacteriophage Therapy in Patients With Prosthetic Joint Infections

    Withdrawn. Checked 2026-10-03. This is a study designed to evaluate bacteriophage therapy in patients with chronic prosthetic joint infections. Randomized Open Label, Parallel Group, Controlled Study to Evaluate the Safety and Surgery Spari

    ProstheticJointKneeHipPhageBacteriophageProsthetic Joint
  13. Therapy studies

    Bacteriophage Therapy TP-102 in Diabetic Foot Ulcers

    Completed. Checked 2026-10-03. This is a Phase I/IIa trial designed to evaluate topical bacteriophage therapy in patients with diabetic foot ulcers. A Double-Blind and Randomized Study to Determine the Safety and Tolerability of Multiple Do

    Bacteriophage therapy
  14. Therapy studies

    Phage Therapy for the Prevention and Treatment of Pressure Ulcers.

    Status unconfirmed. Checked 2026-10-03. This study will evaluate a topical bacteriophage therapy product (BACTELIDE) as an adjunct to standard therapy for the prevention and treatment of pressure ulcers colonized with S. aureus, P. aerugino

    Wound infectionPressure injuryBedsoresPseudomonas aeruginosaKlebsiella pneumoniaeStaphylococcus aureusResistant infectionPhageBacteriophage
  15. Therapy studies

    Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection

    Completed. Checked 2026-10-03. This is a Phase 1b/2a study with the primary objective to determine if BX004-A is safe and tolerable. Exploratory objectives include whether BX004-A reduces sputum Pseudomonas aeruginosa (PsA) bacterial load i

  16. Therapy studies

    Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis

    Terminated. Checked 2026-10-03. This is a phase 2b randomized trial designed to evaluate bacteriophage therapy in subjects with diabetic foot osteomyelitis. Phase 2b Randomized, Parallel, Double-blind, Placebo-Controlled, Repeat Dose, Multi

    DiabetesOsteomyelitisFoot InfectionPhage TreatmentBacteriophagePhageBone Infection
  17. Therapy studies

    Safety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of Shigellosis

    Active, not recruiting. Checked 2026-10-03. The study is a first-in-human Phase 1/2a randomized, double-blind, placebo-controlled trial to assess the clinical safety and efficacy of ShigActive in healthy adults with experimental Shigella ch

    bacteriophagephageShigella
  18. Therapy studies

    Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia

    Completed. Checked 2026-10-03. Phase 1b/2a, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Escalation Study of the Safety, Tolerability, and Efficacy of Intravenous AP SA02 as an Adjunct to Best Available Antibiotic T

    BacteriophagePhageBacteremiaStaphylococcus AureusStaphylococcusSAB
  19. Therapy studies

    A Study of Topical BX005-A in Subjects With Moderate to Severe Atopic Dermatitis

    Withdrawn. Checked 2026-10-03. The purpose of study BMX-05-001 is to evaluate the safety, tolerability, efficacy, and pharmacodynamics of BX005-A compared to vehicle administered topically in adult subjects with moderate to severe atopic de

  20. Therapy studies

    Bacteriophage Therapy in First Time Chronic Prosthetic Joint Infections

    Withdrawn. Checked 2026-10-03. This study will test the feasibility of a regimen of intraoperative (IO) and intravenous (IV) PhageBank™ bacteriophage therapy in conjunction with a DAIR procedure to cure chronic prosthetic joint infection (P

    ProstheticJointKneeHipPhageBacteriophageProsthetic JointDAIR
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