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Felix Biotechnology, South San Francisco is hiring a chief science officer to work closely with their executive team to drive their phage platform & therapeutic portfolio.

Necrotizing enterocolitis is a currently unpreventable life-threatening GI disorder of preterm infants. Fecal microbiota transplantation is promising, but risks transfer of pathogenic microbes. Anders Brunse (University of Copenhagen, Denma

Elyse Stachler (Eawag, Swiss Federal Institute of Aquatic Science and Technology) and colleagues published a new paper in Applied and Environmental Microbiology showing phage treatment before chemical disinfection can enhance removal of pla

Aisling Brady (University of Glasgow, UK) and colleagues published a new paper in Current Biology showing that the arbitrium system controls prophage induction. This mechanism was explored in Bacillus subtilis.

Eric Brown (Harvard Medical School) and colleagues published a paper in Cell Host & Microbe showing that gut microbiome ADP-ribosyltransferases are widespread phage-encoded fitness factors. Previously thought to be restricted to pathogens,

Pawel Markwitz (University of Wroclaw, Poland) and colleagues published a new paper in ISME on genome-driven elucidation of phage-host interplay and the impact of phage resistance evolution on bacterial fitness. They systematically assessed

Dror Shitrit (Israel Institute of Technology, Israel) and colleagues published a paper in ISME Journal on how genetic engineering of marine cyanophages reveals integration but not lysogeny in T7-like cyanophages. They developed a method of

Mar Pérez-Ruiz (National Centre for Biotechnology, Spain) and colleagues published a paper in PNAS on how phage T7 core components assemble to allow DNA translocation across the bacterial envelope. They solved the structures of the core pro

Nicole Rutbeek (University of Manitoba, Canada) and colleagues published a research article in JBC on the molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox. They demonstrated an example of conver

Kristopher Kieft (University of Wisconsin-Madison, USA) published a paper in Cell Reports on virus-associated organosulfur metabolism in human and environmental systems. They reported the discovery of 39 gene families involved in organosulf

Janina Rahlff (University of Duisburg-Essen, Germany) and colleagues published a paper in Nature Communications on how lytic archaeal viruses infect abundant primary producers in Earth’s crust. They used a combination of metagenomics and a

Xiaoqing Wang (Zhejiang University-University of Edinburgh Institute, China) and colleagues published a new preprint on how phage resistance mechanisms increase colistin sensitivity in Acinetobacter baumannii.

Ameneh Khatami (The Children’s Hospital at Westmead and University of Sydney) and colleagues published a new paper in EMBO Molecular Medicine on bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a chi

Matthew Bond (Dartmouth College, USA) published a paper in eLife on how matrix-trapped viruses can prevent invasion of bacterial biofilms by colonizing cells. They showed that T7 phage remains viable when trapped in an E. coli biofilm, and

Audrey Labarde (Université Paris-Saclay, France) and colleagues published a paper in PNAS on temporal compartmentalization of viral infection in bacterial cells. They showed that infection of Bacillus subtilis by phage SPP1 hijacks host rep

Kema Malki (University of South Florida) and colleagues published a paper in AEM on spatial and temporal dynamics of prokaryotic and viral community assemblages in a lotic system. They looked at prokaryotic and viral abundance and diversity

Yue Liu (Wageningen University & Research, Netherlands) and colleagues published a new preprint investigating a phenomenon where massive numbers of lipid-engulfed tailless phage particles are released from Lactococcus lactis without causing

Most lysogeny-associated adaptations are through new gene acquisition, but prophages can also insert into functional genes and impart a benefit by disrupting their expression ('active lysogeny'). Christopher Marshall (Marquette University,

CRISPR-Cas12j is a recently identified family of miniature RNA-guided endonucleases from phages. Arturo Carabias (University of Copenhagen) and colleagues published a new Nature Communications paper on the structure of CRISPR-Cas12j3. This

It's recently been discovered that during replication, some jumbo phages (genomes > 200 kb) establish complex subcellular organization within their host. Vorrapon Chaikeeratisak (University of California San Diego) and colleagues published