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This review describes clinical laboratory barriers to phage therapy in the United States, including inconsistent susceptibility testing and selection, a lack of phage–antibiotic synergy testing, and limited standard methods for testing phag

PhageHostLearn provides pairwise machine-learning models for phage–host interaction prediction, with code for training models, reproducing the study, or making new predictions. PhageHostLearn

The paper introduces PhageDPO, a machine-learning tool available in Galaxy for identifying depolymerases in phage and prophage genomes. The authors say the source code is on GitHub. Computers in Biology and Medicine article

The recombinant PRA33gp45 hydrolysed K27 capsule polysaccharides and inhibited biofilm formation, disrupted mature biofilms, and altered biofilm architecture. In a Galleria mellonella larvae model, PRA33gp45 treatment lowered morbidity and

Broad Institute researchers used phage-assisted evolution to improve the editing efficiency of compact reverse transcriptases by up to 22-fold and generated prime editors 516-810 base pairs smaller than PEmax. The resulting PE6a-g editors e

npj Viruses is inviting submissions to its collection “Phages as antimicrobial therapy”, edited by Ruby CY Lin (The University of Sydney), Sabrina Green (KU Leuven) and Renee Ng (The Kids Research Institute Australia and The University of W