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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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231 news items

  • Tulane Ventures invests $250,000 in Biophoundry to advance engineered phage therapies

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. Updates

    Brouns Lab invites postdoc and PhD inquiries

    If you are interested in postdoc or PhD opportunities, you are welcome to send your CV to Brouns Lab. Postdoc candidates seeking a host laboratory for a personal fellowship can also get in touch. Brouns Lab

    UpdatesCommunityPhDPostdoc
  2. Updates

    PhageGE

    PhageGE is a graphical platform for exploring bacteriophage genomes, with interactive genomic analysis and visualization tools. PhageGE: an interactive web platform for exploratory analysis and visualization of bacteriophage genomes

    UpdatesPapers
  3. Updates

    P9ly study examines a phage lytic enzyme against resistant bacteria

    The study characterizes P9ly, a lytic enzyme from bacteriophage PSD9. In laboratory experiments, it showed bacteriolytic and bactericidal activity against multidrug-resistant Shigella dysenteriae and Staphylococcus aureus strains; combining

    UpdatesPapersPhage EnzymesAntimicrobial Resistance
  4. Updates

    Bacteriophage therapy beyond antibiotics

    This review surveys emerging bacteriophage approaches across infectious and non-infectious diseases, including phage engineering, delivery strategies, and translational research. Bacteriophage therapy beyond antibiotics: emerging innovation

    UpdatesPapers
  5. Updates

    Compassionate-use phage therapy in 20 patients with drug-resistant mycobacterial disease

    A Clinical Infectious Diseases case series screened Mycobacterium isolates from 200 patients for phage susceptibility and gave phages intravenously, by aerosolization or both to 20 patients on a compassionate-use basis. No adverse reactions

    UpdatesPapersPhage TherapyAMR
  6. Updates

    Phanta profiles virus-inclusive gut metagenomes

    Phanta is a workflow for quantifying taxa from short-read human gut metagenomes using a virus-inclusive genome database with integrated taxonomic information. Phanta

    UpdatesToolsBioinformaticsPhage BiologyMicrobiome
  7. Updates

    Bacteriophage genomics: What has five years of INPHARED taught us?

    The 2026 INPHARED snapshot contained 28,777 complete phage genomes, about twice the 2021 collection, but novel species-level diversity did not rise proportionally and host bias persisted. bioRxiv

    UpdatesPapersPhage GenomicsBioinformatics
  8. Updates

    Pseudotyping Bacteriophage P2 Tail Fibers to Extend the Host Range for Biomedical Applications

    The study re-engineered E. coli phage P2 tail fibers with S16 components. The resulting phages were detargeted from native LPS and could infect through S16’s protein receptor, OmpC. PubMed Central

    UpdatesPapersPhage EngineeringPhage-host interactions
  9. Updates

    INPHARED phage genome reference pipeline

    A Perl pipeline for downloading and filtering GenBank phage genomes, extracting taxonomy and host metadata, and generating downstream bioinformatics files. INPHARED repository

    UpdatesToolsBioinformaticsPhage BiologyPhage Genomics
  10. Updates

    Phynteny predicts the functions of unknown phage genes from gene order (synteny)

    Phynteny is an open-source tool from the Edwards Lab (Grigson et al.) that uses a long short-term memory (LSTM) model trained on phage synteny, the conserved gene order across phages, to assign hypothetical phage proteins to a PHROG functio

    UpdatesToolsBioinformaticsPhage Genomics
  11. Updates

    Community spotlight: Phage Research and Advocacy Network

    Based in Abuja, the Phage Research and Advocacy Network brings students, researchers and communities together around phage research, education and advocacy, with interests across health, agriculture and the environment. Phage Research and A

    UpdatesCommunity
  12. Updates

    Ackermann review: problems of electron microscopy for bacteriophages

    Review of bacteriophage electron microscopy by H.-W. Ackermann (Advances in Virus Research, 2012). It argues that the quality of phage TEM micrographs has slipped since the 1970s, citing a survey of about 130 phage papers since 2006 in whic

    UpdatesPapersReviewPhage Biology
  13. Updates

    Phold annotates phage genomes using protein structures

    Phold annotates bacteriophage genomes and metagenomes using protein structural homology. Its README describes translating protein sequences to Foldseek’s 3Di alphabet with ProstT5 before searching protein structures. Phold

    UpdatesToolsBioinformaticsPhage Genomics
  14. Updates

    PhaMer identifies phages in metagenomic data

    PhaMer is a Python library that identifies bacteriophages in metagenomic data using a Transformer model and protein-based vocabulary. The repository says development moved to PhaBOX 2 and that this folder will no longer be maintained. PhaMe

    UpdatesToolsBioinformaticsPhage Biology
  15. Updates

    Application of machine learning in bacteriophage research

    This review surveys machine-learning applications in bacteriophage research, including phage genomics, host interactions, and microbial-community analysis. Application of machine learning in bacteriophage research

    UpdatesPapers
  16. Updates

    Phages.fr annual network conferences

    Phages.fr runs an annual conference series in different French cities, bringing together research teams working on bacteriophages. Phages.fr

    UpdatesCommunitySymposiumPhage Biology
  17. Updates

    Phages.fr Network (Bacteriophage Network France)

    Phages.fr brings together French research teams and partners working across bacteriophage biology, therapy and biocontrol, and shares their research and activities. Phages.fr

    UpdatesCommunityPhage BiologyPhage Therapy
  18. Updates

    PBI-Scope v0.5.0 adds PhageScope GFF3 information

    PBI-Scope v0.5.0 adds PhageScope GFF3 information to the pbi package. PBI-Scope GitHub release v0.5.0

    UpdatesToolsBioinformatics
  19. Updates

    Benchmarking tools for identifying phages in metagenomic data

    The authors benchmarked ten phage identification tools using artificial contigs, a four-phage mock community, and simulated viromes. DeepVirFinder had the highest F1-scores on the artificial contigs and mock community (0.98 and 0.61); most

    UpdatesPapers
  20. Updates

    A century of phage research: Bacteriophages and the shaping of modern biology

    This review traces phage research from Frederick Twort’s 1915 observations through the discoveries that shaped modern biology. PubMed Central

    UpdatesPapersReviewPhage Biology
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