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Some phages attach to bacterial flagella, and thus have to withstand high drag and torque. But how? Joshua Hardy, Rhys Dunstan (Monash University, Australia) and colleagues published a new paper in Nature Communications that provides new in

“What the Phage” combines bacteriophage identification tools with downstream annotation and classification in a parallel Nextflow workflow. It scales to thousands of datasets and helps users assess cases where tools disagree. bioRxiv

Our next PHAVES event will take place Aug. 4 at 11:00 AM EST / 8:30 PM IST. We'll be interviewing Pranav Johri, founder of Vitalis Phage Therapy, about his impressive progress improving access to phage therapy in India. Pranav is also the c

Phage.ai, the interactive platform created by Piotr Tynecki (SLAVIC AI) and Proteon Pharmaceuticals, has released a new update! You can use phage.ai to access 10K phage sequences with extended characteristics (lifecycle, taxonomy, hosts, to

The PhageOption 2020 meeting scheduled to take place in Cartagena, Colombia, in November has been postponed to 2022.

Edison Cano (Mayo Clinic, Minnesota) and colleagues at Adaptive Phage Therapeutics published a new paper in Clinical Infectious Diseases showing the successful treatment of a patient's infected prosthetic knee with phage therapy, allowing t

The phage field has seen mixed results using phages to treat oral pathogens. Sabrina Green (Baylor College of Medicine) and colleagues have uncovered new reasons behind why some phages may be particularly well-suited for gut pathogen target

Patrick Pausch (UC Berkeley) and colleagues have published a new paper in Science on a new 'minimal functional' CRISPR-Cas system comprised of a single 70-kDa protein, CasΦ, that they discovered in phages. This system is active in human and

Kaitlyn Kortright (Yale School of Medicine) and colleagues published a new paper in PNAS showing their use of INSeq screening to rapidly identify candidate phage receptors. They successfully identified receptors for 4 well-characterized pha

Athina Zampara (University of Copenhagen) and colleagues published a new paper in Scientific Reports on the use of phage receptor binding proteins to enable endolysins ("Innolysins") to kill Gram-negative bacteria.

Oluwafolajimi Adesanya and colleagues, who make up a new team of phage researchers from the University of Ibadan in Nigeria, just published their first review paper on phage therapy. The review also includes a unique perspective on phage th

Intralytix is recruiting patients for its Crohn's disease clinical trial out of Mount Sinai Hospital in New York. They will be evaluating patient stool samples for presence of adherent invasive E. coli (AIEC), and if positive, patients will

Phage Directory Our next PHAVES event will be Tuesday, July 21 at 11 AM Eastern, 5 PM CEST (GMT+2). Piotr Tynecki of SLAVIC AI, the creator of phage.ai, will give a talk entitled "Boosting phage exploration by Artificial Intelligence: what

Cassandra Nelson, University of Maryland Next week’s Pseudomonas Seminar will be held on Tuesday July 21th at 1pm EST. Our speaker will be Dr. Patrick Secor from the University of Montana presenting “The intersection of quorum sensing and P

Emmanuel Nnadi, Plateau State University, Nigeria Are you changing lab or upgrading equipment? Consider donating used or old equipment to our phage lab to help us build our phage capacity. Email: eennadi@gmail.com

Emmanuel Nnadi, Plateau State University, Nigeria Would you consider a phage that has acitivity against Staphylococcus aureus, Staphylococcus capitis, Salmonella typhi, Escherichia coli, and Pseudomonas spp an asset or liability? Good phage

Siân Owen (Harvard Medical School) and colleagues published a new preprint on a new prophage-encoded defense protein that simultaneously suppresses phage epidemics in a population (through abortive infection) and provides self-immunity to t

James Gurney (Georgia Institute of Technology) and colleagues published a new paper on 'phage steering': when phages are used to push pathogens to evolve to be less antibiotic-resistant. They show that Pseudomonas phage OMKO1 effectively pu

Intralytix has been issued a US patent covering its Shigella phages and their various formulations and applications (US Patent # 10,711,252), including improving food safety and human health, maintaining healthy gut microflora by modulating

Stanley Ho (University of Birmingham) has made a list of bioinformatics tools for predicting and identifying phages in metagenomes and metaviromes. See also this Twitter thread, where others have been sharing similar tools.