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Kaitlyn Kortright (Yale School of Medicine) and colleagues published a new paper in PNAS showing their use of INSeq screening to rapidly identify candidate phage receptors. They successfully identified receptors for 4 well-characterized phages and for 5/6 newly-isolated phages. Their approach is based on screening transposon mutant libraries under phage pressure to find bacterial genes required for phage infection.

SourceCapsid & Tail #85