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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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  1. UpdatesApr 30, 2021

    Update from the PhageAI crew: We're proud to announce to you the release of PhageAI 0.8.0: extended repository and two new f

    Update from the PhageAI crew: We're proud to announce to you the release of PhageAI 0.8.0: extended repository and two new features: closest phages and Expert form! What's new: - uploading your sample and discovering top-10 closest phages

    UpdatesCommunity
  2. UpdatesApr 30, 2021

    Courtney Davies (Massey University, New Zealand) and colleagues published a new paper in Frontiers in Microbiology showing th

    Courtney Davies (Massey University, New Zealand) and colleagues published a new paper in Frontiers in Microbiology showing that Mycobacteriophage endolysins can kill Mycobacteria when fused to 'PLAN-M' biodegradable nanobeads, which can be

    UpdatesBiotechLysinsResearch paper
  3. UpdatesApr 30, 2021

    Not one but THREE new papers published today in Science on phage DNA modications; they collectively describe a new pathway fo

    Not one but THREE new papers published today in Science on phage DNA modications; they collectively describe a new pathway for purine biosynthesis and substitution of adenine by diaminopurine, found to be widespread in phages! Check out thi

    UpdatesNewsPhage DNA modificationResearch paper
  4. UpdatesApr 30, 2021

    Most tests for Lyme Disease detect antibodies, which are often not present until weeks after infection by the causative patho

    Most tests for Lyme Disease detect antibodies, which are often not present until weeks after infection by the causative pathogen, Borrelia burgdorferi. Jinyu Shan (University of Leicester) published a new paper in Frontiers in Microbiology

    UpdatesDiagnosticsLymeResearch paper
  5. UpdatesApr 30, 2021

    Jutta Kasurinen (University of Helsinki) and colleagues published a paper in Viruses on a new method for screening for phage-

    Jutta Kasurinen (University of Helsinki) and colleagues published a paper in Viruses on a new method for screening for phage-encoded toxic proteins using a Next Generation Sequencing-based assay.

    UpdatesPhage methodsResearch paper
  6. UpdatesApr 30, 2021

    Pappu Mandal (University of Technology Sydney) and colleagues published a new paper in Microbiology showing that phage infect

    Pappu Mandal (University of Technology Sydney) and colleagues published a new paper in Microbiology showing that phage infection of E. coli leads to the formation of membrane vesicles via both explosive cell lysis and membrane blebbing.

    UpdatesResearch paperphage-host interactions
  7. UpdatesApr 23, 2021

    PHAVES #17 will be May 18, 5pm CEST (Paris time). Quentin Lamy-Besnier, a PhD student in the Debarbieux lab at the Institut P

    PHAVES #17 will be May 18, 5pm CEST (Paris time). Quentin Lamy-Besnier, a PhD student in the Debarbieux lab at the Institut Pasteur in Paris will present their team's newly launched Viral Host Range Database, an online tool for recording, a

    UpdatesCommunityVirtual Event
  8. UpdatesApr 23, 2021

    Dear fellow virologists, Welcome to the first conference of the World Society for Virology (WSV), which is a global non-profi

    Dear fellow virologists, Welcome to the first conference of the World Society for Virology (WSV), which is a global non-profit organization established in 2017, to connect virologists around the world, with no restrictions or boundaries, an

    UpdatesCommunityConferenceVirology
  9. UpdatesApr 23, 2021

    Thanks to everyone who attended two exciting forums we helped co-host this week! Yesterday we had 'Phage Therapy UK: Moving t

    Thanks to everyone who attended two exciting forums we helped co-host this week! Yesterday we had 'Phage Therapy UK: Moving toward clinical trials', which brought tons of fruitful conversations among phage-interested medical professionals,

    UpdatesCommunityVirtual EventPhage Directory
  10. UpdatesApr 23, 2021

    Phico Therapeutics was awarded up to 18.2M from CARB-X to pursue phase I clinical trials using its engineered phage-based pla

    Phico Therapeutics was awarded up to 18.2M from CARB-X to pursue phase I clinical trials using its engineered phage-based platform, SASPject™.

    UpdatesBiotech news
  11. UpdatesApr 23, 2021

    Felix Biotechnology, alongside researchers at Yale University (including labs of Paul Turner, Ben Chan and Jon Koff), are rec

    Felix Biotechnology, alongside researchers at Yale University (including labs of Paul Turner, Ben Chan and Jon Koff), are recruiting patients for a cystic fibrosis phage therapy clinical trial! If interested, please contact claire.cochrane@

    UpdatesBiotech newsClinical TrialCystic fibrosisPhage Therapy
  12. UpdatesApr 23, 2021

    Prisca Perlemoine (University Grenoble Alpes, France) and colleagues published a new paper in PLOS ONE on phage susceptibilit

    Prisca Perlemoine (University Grenoble Alpes, France) and colleagues published a new paper in PLOS ONE on phage susceptibility testing and infectious titer determination through wide-field lensless monitoring of phage plaque growth.

    UpdatesPhage methodsResearch paper
  13. UpdatesApr 23, 2021

    Dimitrios Skliros (Agricultural University of Athens, Greece) and colleagues published a new paper in Viruses describing how

    Dimitrios Skliros (Agricultural University of Athens, Greece) and colleagues published a new paper in Viruses describing how the development of phage resistance in Vibrio alginolyticus depends on a complex metabolic adaptation strategy.

    UpdatesPhage resistanceResearch paperphage-host interactions
  14. UpdatesApr 23, 2021

    Martin Loessner and Rob Lavigne co-edited a special issue of Current Opinion in Biotechnology dedicated to phage, entitled Na

    Martin Loessner and Rob Lavigne co-edited a special issue of Current Opinion in Biotechnology dedicated to phage, entitled Nanobiotechnology — Phage Therapy. The issue is now complete: check out the 21 articles here!

    UpdatesBiotechPerspectiveReviewSpecial Issue
  15. UpdatesApr 16, 2021

    Phil Huss (University of Wisconsin-Madison) and colleagues published a new paper in eLife describing their use of deep mutati

    Phil Huss (University of Wisconsin-Madison) and colleagues published a new paper in eLife describing their use of deep mutational scanning to map the functional landscape of the T7 phage receptor binding domain. Using this high-throughput,

    UpdatesReceptor binding proteinResearch paper
  16. UpdatesApr 16, 2021

    Janet Nale and Martha Clokie (University of Leicester) published a new perspective in Current Opinion in Biotechnology on pre

    Janet Nale and Martha Clokie (University of Leicester) published a new perspective in Current Opinion in Biotechnology on preclinical data and safety assessment of phage therapy in humans. They emphasize that safety and efficacy data is nee

    UpdatesPhage TherapyResearch paper
  17. UpdatesApr 16, 2021

    One issue that obstructs phage efficiency in vivo is poor localization of phage to the site of infection. Aurelija Grigonyte

    One issue that obstructs phage efficiency in vivo is poor localization of phage to the site of infection. Aurelija Grigonyte (University of Warwick) and colleagues published a new paper in Pharmaceuticals showing how they modified phages to

    UpdatesEngineered phagesIn vivo interactionsResearch paper
  18. UpdatesApr 16, 2021

    Several high-profile phage therapy clinical trials have failed, leading many to point toward phage formulation and method of

    Several high-profile phage therapy clinical trials have failed, leading many to point toward phage formulation and method of application as being of underappreciated importance. Daniel Rosner (Fixed Phage, Glasgow) and colleagues published

    UpdatesFormulationResearch paper
  19. UpdatesApr 16, 2021

    Ellina Trofimova (Macquarie University, Australia) and colleagues published a new preprint describing Plaque Size Tool: an au

    Ellina Trofimova (Macquarie University, Australia) and colleagues published a new preprint describing Plaque Size Tool: an automated command-line application for plaque analysis, which can simplify and standardize phage plaque morphology me

    UpdatesPreprintTool
  20. UpdatesApr 15, 2021

    The Africa Phage Forum is hosting its next phage webinar in its series, April 23 at 4pm GMT with special guest Dr. Jesca Naka

    The Africa Phage Forum is hosting its next phage webinar in its series, April 23 at 4pm GMT with special guest Dr. Jesca Nakavuma (Veterinarian and Senior Lecturer at Makerere University, Uganda), who will give a talk entitled Practical cha

    UpdatesCommunityVirtual Event
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