Community post

Janet Nale and Martha Clokie (University of Leicester) published a new perspective in Current Opinion in Biotechnology on preclinical data and safety assessment of phage therapy in humans. They emphasize that safety and efficacy data is needed to motivate clinical trials, how in vitro studies can ensure the most promising phages are developed, how human cell line studies can provide key data on human-phage interactions, and how insect and animal models can also inform phage development.