Search

Dimitrios Skliros (Agricultural University of Athens, Greece) and colleagues published a new paper in Viruses describing how the development of phage resistance in Vibrio alginolyticus depends on a complex metabolic adaptation strategy.

Phil Huss (University of Wisconsin-Madison) and colleagues published a new paper in eLife describing their use of deep mutational scanning to map the functional landscape of the T7 phage receptor binding domain. Using this high-throughput,

Janet Nale and Martha Clokie (University of Leicester) published a new perspective in Current Opinion in Biotechnology on preclinical data and safety assessment of phage therapy in humans. They emphasize that safety and efficacy data is nee

One issue that obstructs phage efficiency in vivo is poor localization of phage to the site of infection. Aurelija Grigonyte (University of Warwick) and colleagues published a new paper in Pharmaceuticals showing how they modified phages to

Several high-profile phage therapy clinical trials have failed, leading many to point toward phage formulation and method of application as being of underappreciated importance. Daniel Rosner (Fixed Phage, Glasgow) and colleagues published

David Sáez Moreno (PhagoMed) and colleagues published a new paper on naturally-bred 'ε2-phages'. They used the Appelman's protocol to train S. aureus phages to massively broaden host range and increase virulence. Surprisingly, they showed t

Łukasz Richter (Polish Academy of Sciences) and colleagues published a new paper in Scientific Reports looking at phage adsorption to polypropylene labware and the effects this could have on phage research reproducibility.

Marion Bichet (Monash University) and colleagues published a new paper in IScience showing that phage uptake by mammalian cell layers represents a potential sink that may impact phage therapy. Check out Jeremy Barr's Tweet thread on the pap

Abbas Soleimani-Delfan (University of Isfahan) and colleagues published a new paper in Journal of Virological Methods showing a rapid new method for phage genomic DNA extraction.

Sean Carim (UC Berkeley) and colleagues published a new paper in The ISME Journal on their systematic discovery of pseudomonad genetic factors involved in sensitivity to tailocins ('headless phages'!). Read also this SciTechDaily article th

Eleanor Townsend (University of Warwick) and colleagues published a new paper in PHAGE describing the isolation and characterization of 30 novel, genetically diverse Klebsiella phages.

Dann Turner (University of the West of England) and colleagues published a new paper in Viruses entitled A Roadmap for Genome-Based Phage Taxonomy. See also this Twitter thread by Evelien Adriaenssens.

Carol Zhou (Lawrence Livermore National Laboratory) and colleagues published a new paper in G3 Genes|Genomes|Genetics entitled MultiPhATE2: Code for functional annotation and comparison of phage genomes.

Danish Malik (Loughborough University) and colleagues published a new paper in Current Opinion in Biotechnology showing current approaches for manufacture, formulation, targeted delivery and controlled release of phage-based therapeutics.

Ryan Cook (University of Nottingham) and colleagues published a new paper in Microbiome showing how a hybrid assembly of an agricultural slurry virome revealed a diverse and stable community with the potential to alter the metabolism and vi

Steven Sutcliffe (McGill University), Michael Shamash and colleagues published a new paper in Viruses showing how common medications lead to prophage induction in human gut bacteria. They tested anti-inflammatory, chemotherapy, mild analges

Milan Gerovac (University of Würzburg, Germany) and colleagues published a new paper in MBio — they used Grad-seq (gradient profiling by sequencing) to get a comprehensive view of RNA and protein complexes in Pseudomonas aeruginosa under st

Karishma Bisht (Texas Tech University) and colleagues published a new paper in npj Biofilms and Microbiomes showing the impact of temperature-dependent phage expression on Pseudomonas aeruginosa biofilm formation. Their work suggests that p

Brandon Berryhill (Emory University) and colleagues published a research article exploring potential efficacy of a phage seemingly ideal for combined phage and antibiotic treatment. Although the phage PYO^Sa is able to kill S. aureus at hig

Fazal Mehmood Khan (Chinese Academy of Sciences) and colleagues published a research paper on a novel endolysin isolated from an Acinetobacter baumannii phage with high antibacterial activity against multiple gram-negative microbes. The nov