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  1. UpdatesJun 11, 2021

    Tridib Mahata (Tel Aviv University) and colleagues published a new paper in PNAS showing a new phage mechanism for selective

    Tridib Mahata (Tel Aviv University) and colleagues published a new paper in PNAS showing a new phage mechanism for selective nicking of dUMP-containing DNA.

    UpdatesPhage DNA modificationResearch paper
  2. UpdatesJun 4, 2021

    Valuable phages have good shelf-life properties, but how can we reliably characterize the structural parts of the phage parti

    Valuable phages have good shelf-life properties, but how can we reliably characterize the structural parts of the phage particle? Tze Thung (Centre to Impact AMR, Monash University) and colleagues published a new mSystems paper on their new

    UpdatesMachine learningResearch paperStructural BiologyTool
  3. UpdatesJun 4, 2021

    Branko Rihtman (University of Warwick) and colleagues have published a new paper in Current Biology on their identification o

    Branko Rihtman (University of Warwick) and colleagues have published a new paper in Current Biology on their identification of an unusual nucleotide substitution from deoxythymidine to deoxyuridine in a novel family of phages belonging to N

    UpdatesPhage DNA modificationResearch paper
  4. UpdatesMay 28, 2021

    Carlos Guerrero-Bustamante (University of Pittsburgh) and colleagues published a new paper in MBio showing their progress tow

    Carlos Guerrero-Bustamante (University of Pittsburgh) and colleagues published a new paper in MBio showing their progress toward developing a phage cocktail for tuberculosis; using genome engineering and phage genetics, they have created a

    UpdatesPhage cocktail developmentPhage engineeringResearch paper
  5. UpdatesMay 28, 2021

    Graça Pinto (University of Minho) and colleagues published a new paper in BMC Genomics showing insights into the genome archi

    Graça Pinto (University of Minho) and colleagues published a new paper in BMC Genomics showing insights into the genome architecture and evolution of Shiga toxin encoding phages of E. coli.

    UpdatesPhage genomicsResearch paper
  6. UpdatesMay 28, 2021

    Shakhinur Islam Mondal (APC Microbiome Ireland) and colleagues published a new paper in International Journal of Molecular Sc

    Shakhinur Islam Mondal (APC Microbiome Ireland) and colleagues published a new paper in International Journal of Molecular Sciences that characterizes a Clostridioides difficile-specific endolysin that affects spore outgrowth.

    UpdatesLysinsResearch paper
  7. UpdatesMay 21, 2021

    Danielle Campbell (University of Illinois) and colleagues published a new paper in Cell Reports showing that infection with B

    Danielle Campbell (University of Illinois) and colleagues published a new paper in Cell Reports showing that infection with Bacteroides phage BV01 alters the host transcriptome and bile acid metabolism. News article | Paper

    UpdatesGut phagePhage-host interactionsResearch paper
  8. UpdatesMay 21, 2021

    Wai Hoe Chin (Monash University) and colleagues published a new preprint showing phage adaptation to a mammalian mucosa revea

    Wai Hoe Chin (Monash University) and colleagues published a new preprint showing phage adaptation to a mammalian mucosa reveals a trans–domain evolutionary axis. Paper | Tweet thread

    UpdatesGut phageMammalian hostPreprintResearch paper
  9. UpdatesMay 21, 2021

    Betty Shen (Fred Hutchinson Cancer Research Center) and colleagues published a new paper in Structure showing coordination of

    Betty Shen (Fred Hutchinson Cancer Research Center) and colleagues published a new paper in Structure showing coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualize

    UpdatesResearch paperStructural Biology
  10. UpdatesMay 21, 2021

    Colin Lam (Roche Molecular Systems) and colleagues published a new paper in ACS Synthetic Biology showing a tail fiber engine

    Colin Lam (Roche Molecular Systems) and colleagues published a new paper in ACS Synthetic Biology showing a tail fiber engineering platform for improved bacterial transduction-based diagnostic reagents.

    UpdatesResearch paperSynthetic biology
  11. UpdatesMay 7, 2021

    Ryan Cook (University of Nottingham) and colleagues published a new paper describing INfrastructure for a PHAge REference Dat

    Ryan Cook (University of Nottingham) and colleagues published a new paper describing INfrastructure for a PHAge REference Database (INPHARED): a way to identify large-scale biases in the current collection of phage genomes. It includes a sc

    UpdatesBioinformaticsPhage genomicsPreprintResearch paper
  12. UpdatesMay 7, 2021

    Larissa Kever (Forschungszentrum Jülich, Germany) and colleagues published a new preprint showing that aminoglycoside antibio

    Larissa Kever (Forschungszentrum Jülich, Germany) and colleagues published a new preprint showing that aminoglycoside antibiotics inhibit phage infection by blocking an early step of the phage infection cycle. Paper | Tweet thread by Aël Ha

    UpdatesResearch paper
  13. UpdatesMay 7, 2021

    Mihnea Mangalea (University of Colorado School of Medicine) and colleagues published a new paper in Cell Host & Microbe showi

    Mihnea Mangalea (University of Colorado School of Medicine) and colleagues published a new paper in Cell Host & Microbe showing that individuals at risk for rheumatoid arthritis harbor differential intestinal phage communities with distinct

    UpdatesGut phageResearch paper
  14. UpdatesMay 7, 2021

    Keiko Salazar (Baylor College of Medicine) and colleagues published a new paper in MBio showing antiviral resistance and phag

    Keiko Salazar (Baylor College of Medicine) and colleagues published a new paper in MBio showing antiviral resistance and phage counter adaptation to antibiotic-resistant Extraintestinal Pathogenic E. coli.

    UpdatesResearch paperphage-host interactions
  15. UpdatesApr 30, 2021

    Courtney Davies (Massey University, New Zealand) and colleagues published a new paper in Frontiers in Microbiology showing th

    Courtney Davies (Massey University, New Zealand) and colleagues published a new paper in Frontiers in Microbiology showing that Mycobacteriophage endolysins can kill Mycobacteria when fused to 'PLAN-M' biodegradable nanobeads, which can be

    UpdatesBiotechLysinsResearch paper
  16. UpdatesApr 30, 2021

    Not one but THREE new papers published today in Science on phage DNA modications; they collectively describe a new pathway fo

    Not one but THREE new papers published today in Science on phage DNA modications; they collectively describe a new pathway for purine biosynthesis and substitution of adenine by diaminopurine, found to be widespread in phages! Check out thi

    UpdatesNewsPhage DNA modificationResearch paper
  17. UpdatesApr 30, 2021

    Most tests for Lyme Disease detect antibodies, which are often not present until weeks after infection by the causative patho

    Most tests for Lyme Disease detect antibodies, which are often not present until weeks after infection by the causative pathogen, Borrelia burgdorferi. Jinyu Shan (University of Leicester) published a new paper in Frontiers in Microbiology

    UpdatesDiagnosticsLymeResearch paper
  18. UpdatesApr 30, 2021

    Jutta Kasurinen (University of Helsinki) and colleagues published a paper in Viruses on a new method for screening for phage-

    Jutta Kasurinen (University of Helsinki) and colleagues published a paper in Viruses on a new method for screening for phage-encoded toxic proteins using a Next Generation Sequencing-based assay.

    UpdatesPhage methodsResearch paper
  19. UpdatesApr 30, 2021

    Pappu Mandal (University of Technology Sydney) and colleagues published a new paper in Microbiology showing that phage infect

    Pappu Mandal (University of Technology Sydney) and colleagues published a new paper in Microbiology showing that phage infection of E. coli leads to the formation of membrane vesicles via both explosive cell lysis and membrane blebbing.

    UpdatesResearch paperphage-host interactions
  20. UpdatesApr 23, 2021

    Prisca Perlemoine (University Grenoble Alpes, France) and colleagues published a new paper in PLOS ONE on phage susceptibilit

    Prisca Perlemoine (University Grenoble Alpes, France) and colleagues published a new paper in PLOS ONE on phage susceptibility testing and infectious titer determination through wide-field lensless monitoring of phage plaque growth.

    UpdatesPhage methodsResearch paper
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