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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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231 news items

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesMar 10, 2023

    The documentary, Salt in My Soul, follows the life of Mallory Smith, who was diagnosed with cystic fibrosis at age 3, and a r

    The documentary, Salt in My Soul, follows the life of Mallory Smith, who was diagnosed with cystic fibrosis at age 3, and a resistant infection at age 15. In her final days, her father attempted to arrange phage therapy for her, but it was

    UpdatesCommunityAMRIn-person eventDocumentary
  2. UpdatesMar 10, 2023

    In this study, Benjamin A. Adler (University of California, Berkeley) and colleagues used a high-throughput genetic screen to

    In this study, Benjamin A. Adler (University of California, Berkeley) and colleagues used a high-throughput genetic screen to uncover genome-wide host suppressors of diverse single-gene lysis proteins (Sgls). See also this interview with th

    UpdatesPhage-host interactionsResearch paper
  3. UpdatesMar 10, 2023

    Screen Australia has announced $4.6 million in production funding for 21 documentaries, including A Forgotten Cure (working t

    Screen Australia has announced $4.6 million in production funding for 21 documentaries, including A Forgotten Cure (working title), a 54-minute phage therapy documentary that follows teams of scientists in Melbourne and Sydney (part of Phag

    UpdatesPhage therapyScience communication
  4. UpdatesMar 10, 2023

    A new paper in Nature Microbiology by Madison C. Williams (University of Washington) and colleagues entitled Restriction endo

    A new paper in Nature Microbiology by Madison C. Williams (University of Washington) and colleagues entitled Restriction endonuclease cleavage of phage DNA enables resuscitation from Cas13-induced bacterial dormancy reports that restriction

    UpdatesResearch paperType VI CRISPR
  5. UpdatesMar 10, 2023

    In a new preprint, Enea Maffei (University of Basel) and colleagues describe a new phage, Paride, which is able to kill dorma

    In a new preprint, Enea Maffei (University of Basel) and colleagues describe a new phage, Paride, which is able to kill dormant, antibiotic-tolerant bacteria. They suggest that this phage hijacks weak spots in the dormant physiology of anti

    UpdatesPhage-host interactionsResearch paper
  6. UpdatesMar 10, 2023

    In this JAMA Medical News & Perspectives article, Eli Cahan discusses the resurgence of interest in phage therapy in the wake

    In this JAMA Medical News & Perspectives article, Eli Cahan discusses the resurgence of interest in phage therapy in the wake of the COVID-19 pandemic.

    UpdatesPerspectivePhage therapy
  7. UpdatesMar 10, 2023

    The Good Virus is a new book by Tom Ireland that tells the story of phage research, from its beginnings to the present day. N

    The Good Virus is a new book by Tom Ireland that tells the story of phage research, from its beginnings to the present day. Now available for preorder in the UK and the US!

    UpdatesCommunityPhage researchBook
  8. Capsid & TailMar 3, 2023

    CreatiPhage – The Pioneer in China

    Adam Yang, an intern at Shanghai Institute of Phage, interviewed the co-founder of CreatiPhage, Nannan Wu. CreatiPhage is the first company applying phage therapy to humans in China, and seeks to promote the overall development of phage the

    Clinical Trials and Case StudiesIntellectual Property and CommercializationPhage Therapy Access and ImplementationProducts
  9. JobsMar 3, 2023

    The University of Edinburgh is seeking a PhD student to study how the globally disseminated multi-drug resistant E. coli ST13

    The University of Edinburgh is seeking a PhD student to study how the globally disseminated multi-drug resistant E. coli ST131 resists phage treatment while infecting the mammalian bladder, using a pig model of urinary tract infection (this

    JobsPhD projectPhage therapy
  10. JobsMar 3, 2023

    We are looking to hire a part time laboratory technician with a background in microbiology; experience with clinical samples

    We are looking to hire a part time laboratory technician with a background in microbiology; experience with clinical samples or phages is a plus but not required. We are a highly translational team involving close connections with clinician

    JobsPhage therapyLaboratory Technician
  11. JobsMar 3, 2023

    We are looking for a highly motivated & collaborative postdoc to work in our translational team of clinicians & researchers a

    We are looking for a highly motivated & collaborative postdoc to work in our translational team of clinicians & researchers at 80-100% for 1 yr on our clinical phage therapy projects for the treatment of UTIs. Experience with phages & in ce

    JobsPhage therapyPost Doc
  12. JobsMar 3, 2023

    The University of Sheffield is looking for a student to join their research team and work on the development of phage therapy

    The University of Sheffield is looking for a student to join their research team and work on the development of phage therapy for use in AMR Diabetic foot infections.

    JobsDiabetic foot infectionsPhD projectPhage therapy
  13. CommunityMar 3, 2023

    Community
  14. UpdatesMar 3, 2023

    Our @PhageFiles podcast is finally here! Tune in on Spotify, Google Podcasts, Deezer and Amazon Music to listen to our first

    Our @PhageFiles podcast is finally here! Tune in on Spotify, Google Podcasts, Deezer and Amazon Music to listen to our first episodes. In our podcast we will discuss all things phage. You will hear from researchers and entrepreneurs interes

    UpdatesCommunityPhage historyPodcast
  15. UpdatesMar 3, 2023

    ESCMID (European Society of Clinical Microbiology and Infectious Diseases) is hosting a hands-on course on phage therapy 25 -

    ESCMID (European Society of Clinical Microbiology and Infectious Diseases) is hosting a hands-on course on phage therapy 25 - 27 July 2023, Brussels, Belgium) -- register by 06 June 2023 (25 spaces only!).

    UpdatesCommunityCoursePhage therapy
  16. UpdatesMar 3, 2023

    BiomX Inc. announced positive results from Part 1 of the Phase 1b/2a trial evaluating their novel phage cocktail, BX004, for

    BiomX Inc. announced positive results from Part 1 of the Phase 1b/2a trial evaluating their novel phage cocktail, BX004, for the treatment of chronic pulmonary infections caused by Pseudomonas aeruginosa in patients with cystic fibrosis.

    UpdatesBiotech newsClinical Trial
  17. UpdatesMar 3, 2023

    In a new paper in Viruses, Sandrine Le Guellec and colleagues describe a preclinical study involving macaques to predict the

    In a new paper in Viruses, Sandrine Le Guellec and colleagues describe a preclinical study involving macaques to predict the efficacy of delivery of nebulizer-administered Pseudomonas aeruginosa phages during mechanical ventilation. They fo

    UpdatesPhage deliveryResearch paperPhage therapy
  18. UpdatesMar 3, 2023

    In a new paper in Food Microbiology, Marta Volpi and colleagues report on a full-scale industrial trial to evaluate the effic

    In a new paper in Food Microbiology, Marta Volpi and colleagues report on a full-scale industrial trial to evaluate the efficacy of a commercial phage product to reduce the prevalence of naturally occurring Salmonella on pork carcasses. The

    UpdatesIndustrial trialPhage in agricultureResearch paper
  19. UpdatesMar 3, 2023

    In a new paper in Nature Microbiology, Charles Dulberger and colleagues show that the mycobacterial nucleoid-associated prote

    In a new paper in Nature Microbiology, Charles Dulberger and colleagues show that the mycobacterial nucleoid-associated protein Lsr2 is required for productive mycobacteriophage infection.

    UpdatesPhage-host interactionsResearch paper
  20. UpdatesMar 3, 2023

    A new paper in PNAS by Bin Li and colleagues discusses how viruses require the small polyamine spermidine to replicate normal

    A new paper in PNAS by Bin Li and colleagues discusses how viruses require the small polyamine spermidine to replicate normally, in part due to its important role in ribosomal translation. They found genes in many phages and eukaryotic viru

    UpdatesMetabolismPhage biologyResearch paper
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