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  1. UpdatesSep 22, 2023

    Contrafect, a company developing ‘direct lytic agents’ (which include lysins and amurin peptides), has submitted an IND appli

    Contrafect, a company developing ‘direct lytic agents’ (which include lysins and amurin peptides), has submitted an IND application for preliminary approval of a new IV antibacterial agent for treatment of hospital-acquired and ventilator-a

    UpdatesINDBiotech newsLysins
  2. UpdatesSep 22, 2023

    Benjamin Adler and colleagues have developed a broad-spectrum phage functional genomics platform using programmable RNA-bindi

    Benjamin Adler and colleagues have developed a broad-spectrum phage functional genomics platform using programmable RNA-binding protein dRfxCas13d, uncovering hidden infection strategies and predicting over 90 essential genes in phage genom

    UpdatesCRISPRi-ARTPhage engineeringPreprint
  3. UpdatesSep 22, 2023

    Jingxian Yang and colleagues have discovered that agr (quorum sensing) induction reduces expression of tarM (which encodes a

    Jingxian Yang and colleagues have discovered that agr (quorum sensing) induction reduces expression of tarM (which encodes a glycosyltransferase responsible for modification of the major S. aureus phage receptor). This allows lytic phage St

    UpdatesResearch paperPhage susceptibilityQuorum sensing
  4. UpdatesSep 22, 2023

    Phables, a new computational method developed by Vijini Mallawaarachchi and colleagues, resolves phage genomes from fragmente

    Phables, a new computational method developed by Vijini Mallawaarachchi and colleagues, resolves phage genomes from fragmented viral metagenome assemblies, enabling the recovery of over 49% more high-quality phage genomes compared to existi

    UpdatesBioinformatics toolComparative GenomicsViral Identification
  5. UpdatesSep 20, 2023

    Halomonas phage vB_HmeY_H4907 from the Mariana Trench is the deepest isolated siphovirus

    Researchers led from the Ocean University of China characterised Halomonas phage vB_HmeY_H4907, isolated from surface sediment of the Mariana Trench at a depth of 8,900 m. The authors describe it as the deepest isolated siphovirus from the

    UpdatesPapersPhage Biology
  6. UpdatesSep 20, 2023

    Virus-based pyroelectricity: engineered M13 phage generates an electrical potential from heat

    University of California, Berkeley researchers report the first observation of heat-induced electrical potential generation on a virus, studying the pyroelectric properties of the M13 phage. Modifying the pVIII coat protein with different n

    UpdatesPapersPhage Engineering
  7. JobsSep 18, 2023

    PhD position: phage and oncolytic virotherapy at Leiden University in Leiden. Contact Dr. Tingjie Guo, t.guo@lacdr.leidenuniv

    PhD position: phage and oncolytic virotherapy at Leiden University in Leiden. Contact Dr. Tingjie Guo, t.guo@lacdr.leidenuniv.nl.

    Jobs
  8. Capsid & TailSep 15, 2023

    Urine Good Hands: Battling UTIs with Engineered Phages

    This week, we have an amazing guest article from Matthew Dunne and the Loessner Lab at ETH Zurich about their phage-based diagnostic tool and engineered phage work. Recently, the phage engineering team within the group of Prof. Martin Loess

    Phage Therapy ApplicationsTechnical Aspects of Phage ResearchPhage Community and Collaboration
  9. JobsSep 15, 2023

    Westmead Institute for Medical Research, Sydney, Australia is hiring a Clinical Operations Coordinator to support the develop

    Westmead Institute for Medical Research, Sydney, Australia is hiring a Clinical Operations Coordinator to support the development and implementation of phage therapy clinical trials.

    JobsClinical Operations CoordinatorPhage Therapy
  10. JobsSep 15, 2023

    National University of Singapore is hiring a Research Assistant to work on a project involving microbiology work with anaerob

    National University of Singapore is hiring a Research Assistant to work on a project involving microbiology work with anaerobes and phages.

    JobsMicrobiologyImmunologyResearch assistant
  11. JobsSep 15, 2023

    Leibniz Institute on Aging, Germany is hiring a postdoc to study phage-microbiome interactions.

    Leibniz Institute on Aging, Germany is hiring a postdoc to study phage-microbiome interactions.

    JobsMicrobiomePostdoc
  12. JobsSep 15, 2023

    University of Lincoln, UK is hiring a postdoc in Food Science and Microbiology to study phage therapy in foodborne pathogens.

    University of Lincoln, UK is hiring a postdoc in Food Science and Microbiology to study phage therapy in foodborne pathogens.

    JobsFood ScienceMicrobiologyPostdoc
  13. JobsSep 15, 2023

    Lund University, Sweden, is hiring a PhD student to study the role of phage-carried antibiotic resistance genes during epidem

    Lund University, Sweden, is hiring a PhD student to study the role of phage-carried antibiotic resistance genes during epidemic and endemic cholera outbreaks.

    JobsPhage therapyPhD project
  14. JobsSep 15, 2023

    Lawrence Berkeley National Laboratory, Berkeley, California, USA is hiring a project scientist, a postdoc, and a research ass

    Lawrence Berkeley National Laboratory, Berkeley, California, USA is hiring a project scientist, a postdoc, and a research associate for its newly funded Phage Foundry program. Read more about the vision here.

    JobsPostdocResearch associatephage-host interactions
  15. UpdatesSep 15, 2023

    Did you know that VoM is heading down under? The Viruses of Microbes (VoM) Conference will take place in Cairns, Queensland,

    Did you know that VoM is heading down under? The Viruses of Microbes (VoM) Conference will take place in Cairns, Queensland, Australia, July 15-19th, 2024. Registration is open now!

    UpdatesCommunityViruses of MicrobesISVMConference
  16. UpdatesSep 15, 2023

    Katelyn McNair, the creator of Phanotate, has introduced a new tool called Genotate, designed to identify and predict coding

    Katelyn McNair, the creator of Phanotate, has introduced a new tool called Genotate, designed to identify and predict coding genes in phage genomes. Now in final stages of development, it’s built to take your phage genome annotation and an

    UpdatesCommunityBioinformatics toolPhage GenomicsGenome Annotation
  17. UpdatesSep 15, 2023

    Intralytix has announced the launch of a Phase 1/2a clinical trial of its VRELysin™ phage preparation to assess safety and ef

    Intralytix has announced the launch of a Phase 1/2a clinical trial of its VRELysin™ phage preparation to assess safety and efficacy in healthy and VRE-colonized subjects at UPMC in Pittsburgh, Pennsylvania.

    UpdatesPhage therapyClinical TrialBiotech news
  18. UpdatesSep 15, 2023

    A new Canadian phage CRO, Qeen Bio is offering a variety of services including phage characterization, cell banking, fermenta

    A new Canadian phage CRO, Qeen Bio is offering a variety of services including phage characterization, cell banking, fermentation, downstream processing, formulation, lab services for phage clinical trials, and regulatory consulting for pha

    UpdatesPhage CharacterizationFormulation ServicesBiotech news
  19. UpdatesSep 15, 2023

    Erin Attrill (University of Exeter) and colleagues found that slow-growing E. coli cells survive phage T4 in isolation, but f

    Erin Attrill (University of Exeter) and colleagues found that slow-growing E. coli cells survive phage T4 in isolation, but fast-growing cells survive when surrounded by their clonal kin cells.

    UpdatesResearch paperPhage-host interactions
  20. UpdatesSep 15, 2023

    Pedro Leao (University of Texas, Austin) and colleagues have determined that the Asgardarchaeota, a group of archaea related

    Pedro Leao (University of Texas, Austin) and colleagues have determined that the Asgardarchaeota, a group of archaea related to eukaryotes, played important roles in the evolution of viral protection in eukaryotes.

    UpdatesArchaeaEukaryotesDefense Systems
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