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  1. UpdatesDec 8, 2023

    Eligo Bioscience has raised $30 million to advance and test their CRISPR-based medicine for acne vulgaris and develop their p

    Eligo Bioscience has raised $30 million to advance and test their CRISPR-based medicine for acne vulgaris and develop their platform for other diseases. Congrats Eligo!

    UpdatesGenetic MedicinesBiotech newsFunding news
  2. UpdatesDec 8, 2023

    Phages in space!! Phil Huss (University of Wisconsin-Madison) and colleagues discovered that phage-host interactions in micro

    Phages in space!! Phil Huss (University of Wisconsin-Madison) and colleagues discovered that phage-host interactions in microgravity onboard the International Space Station have unique dynamics. They saw significant differences in mutationa

    UpdatesResearch paperPhage in spacePhage-host interactions
  3. UpdatesDec 8, 2023

    Ana Georgina Cobián Güemes (University of California San Diego) and colleagues discovered that jumbo phages are effective aga

    Ana Georgina Cobián Güemes (University of California San Diego) and colleagues discovered that jumbo phages are effective against extensively drug-resistant (XDR) Pseudomonas aeruginosa infections in contaminated preservative-free eyedrops.

    UpdatesResearch PaperJumbo phagesEyedrop outbreak
  4. UpdatesDec 8, 2023

    Abdulkerim Karaynir (Recombinant DNA and Recombinant Protein Center, Turkey) and colleagues have demonstrated the successful

    Abdulkerim Karaynir (Recombinant DNA and Recombinant Protein Center, Turkey) and colleagues have demonstrated the successful transformation of environmental DNA into an active phage in E. coli.

    UpdatesPhage rebootingSynthetic biologyResearch paper
  5. UpdatesDec 4, 2023

    Genome-wide CRISPRi essentiality mapping in phages λ and P1 identifies sites for DNA barcoding

    Researchers at the University of California, Berkeley developed a CRISPR interference method to map gene essentiality in phages and applied it to the coliphages λ and P1, largely recapitulating the known essential genes of λ and giving new

    UpdatesPapersPhage GenomicsPhage Engineering
  6. UpdatesDec 2, 2023

    Engineered fd phages bind copper ions for possible bioremediation

    Researchers at KIST Europe genetically modified filamentous fd phages to display shortened versions of a Cu(II)-specific peptide (HGFANVA). ICP-MS analyses showed improved Cu(II) binding by the engineered phages compared with wild-type fd,

    UpdatesPapersPhage Engineering
  7. Capsid & TailDec 1, 2023

    Lessons from viral vectors, CAR-T, & RNA

    Phage production has its quirks, but it’s not the only field trying to reliably manufacture a new biological entity. This week Jessica shares learnings from Australia’s annual bioprocessing conference about challenges other fields are facin

    Phage Production and ManufacturingTechnical Aspects of Phage ResearchTools
  8. JobsDec 1, 2023

    The Le Roux lab in Montréal, Canada is hiring a phage postdoc to unravel the fundamental principles of phage-bacteria coevolu

    The Le Roux lab in Montréal, Canada is hiring a phage postdoc to unravel the fundamental principles of phage-bacteria coevolution in natural populations, focusing on marine bacteria within the Vibrionaceae family.

    JobsPostdocBasic ResearchCoevolution
  9. JobsDec 1, 2023

    The AIM Doctoral Training program (Birmingham, Leicester, Nottingham) has a range of openings for PhD students open for appli

    The AIM Doctoral Training program (Birmingham, Leicester, Nottingham) has a range of openings for PhD students open for application.

    JobsPhD project
  10. JobsDec 1, 2023

    University of California, Irvine, Irvine, USA, is hiring an Associate/ Full Professor of Virology in Molecular Biology & Bioc

    University of California, Irvine, Irvine, USA, is hiring an Associate/ Full Professor of Virology in Molecular Biology & Biochemistry (Tenure-Track) to specialize in the study of phage-related host-virus interactions, viral pathogenesis, an

    JobsFacultyVirology
  11. JobsDec 1, 2023

    Justin Meyer (UC San Diego) is hiring 2 postdocs to work on subjects at the intersection of basic research on phage-bacterial

    Justin Meyer (UC San Diego) is hiring 2 postdocs to work on subjects at the intersection of basic research on phage-bacterial coevolution and phage therapy.

    JobsPostdocBasic ResearchCoevolution
  12. UpdatesDec 1, 2023

    Phages for Global Health's president, Dr. Tobi Nagel, has been selected as 1 of 22 Fulbright Global Scholars in this year's c

    Phages for Global Health's president, Dr. Tobi Nagel, has been selected as 1 of 22 Fulbright Global Scholars in this year's cohort! Funded by the US Congress, Tobi’s project will help establish phage regulatory systems in Africa and Asia b

    UpdatesCommunityFulbright Global ScholarsGlobal Health
  13. UpdatesDec 1, 2023

    UC San Diego's Center for Innovative Phage Applications and Therapeutics (IPATH) is launching the Phage Therapy Clinical Supp

    UC San Diego's Center for Innovative Phage Applications and Therapeutics (IPATH) is launching the Phage Therapy Clinical Support Fund to increase accessibility to phage therapy for patients worldwide who require compassionate use of phages.

    UpdatesCommunityPhage TherapyAntibiotic-Resistant InfectionsClinical Support Fund
  14. UpdatesDec 1, 2023

    On a new episode of the Accelerating Success podcast, Dr. Steven Theriault discusses how regulatory hurdles in Canada hinder

    On a new episode of the Accelerating Success podcast, Dr. Steven Theriault discusses how regulatory hurdles in Canada hinder access to innovative animal health products, leading Cytophage Technologies to decide against bringing their produc

    UpdatesCommunityCanadaAnimal HealthRegulatoryPodcast
  15. UpdatesDec 1, 2023

    Phage.ai has developed a Python package! PhageAI is an AI-driven software platform for prediction of phage lifecycle and taxo

    Phage.ai has developed a Python package! PhageAI is an AI-driven software platform for prediction of phage lifecycle and taxonomy, providing valuable insights into phage characteristics and protein structural classes classification. Try it

    UpdatesCommunityAIPython PackageComputational tools
  16. UpdatesDec 1, 2023

    If you are using iPHoP for phage host prediction: a new update has just been released (1.3.3), alongside an updated host data

    If you are using iPHoP for phage host prediction: a new update has just been released (1.3.3), alongside an updated host database now based on GTDB r214. Updated code and database available via conda / Docker. Report any issues here.

    UpdatesCommunityResearch PaperPhage-Host PredictionGenomic Analysis
  17. UpdatesDec 1, 2023

    BiomX announced positive results from their Phase 1b/2a trial evaluating BX004, a P. aeruginosa phage cocktail, in cystic fib

    BiomX announced positive results from their Phase 1b/2a trial evaluating BX004, a P. aeruginosa phage cocktail, in cystic fibrosis patients. They saw clinical improvement in pulmonary function and reduced bacterial burden, paving the way fo

    UpdatesBiotech newsClinical trialPhage therapy
  18. UpdatesDec 1, 2023

    Tired of doing plaque assays? Check out the Bollyky lab’s new method to count phages and assess their bioactivity using a DLS

    Tired of doing plaque assays? Check out the Bollyky lab’s new method to count phages and assess their bioactivity using a DLS Particle Size Analyzer, now published in PNAS. Great tweet thread here!

    UpdatesResearch PaperDynamic Light ScatteringPhage methods
  19. UpdatesDec 1, 2023

    A recent multi-specialty survey in the United Kingdom revealed substantial demand and willingness among clinicians to use pha

    A recent multi-specialty survey in the United Kingdom revealed substantial demand and willingness among clinicians to use phage therapy in appropriate cases.

    UpdatesPhage TherapyAntibiotic ResistanceSurvey
  20. UpdatesDec 1, 2023

    Baptiste Gaborieau (Université Paris Cité, France) and colleagues published a new preprint on predicting diverse phage bacter

    Baptiste Gaborieau (Université Paris Cité, France) and colleagues published a new preprint on predicting diverse phage bacteria-interactions at the strain level from their genomes only. They created a matrix of >38k phage-bacteria interacti

    UpdatesResearch PaperPhage InteractionsPredictive Algorithms
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