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The Japanese government is moving forward with a pull incentive for developing new antibiotics, called the Antimicrobial Securement Project. According to CARB-X's director, Kevin Outterson, this is a revenue guarantee pull incentive, akin t

In a new Nature Microbiology paper, Jan Wohlfarth (ETH Zurich) and colleagues show that Listeria and Enterococcus can evade phage predation by transient conversion to a cell wall-deficient L-form state, which is triggered by endolysins disi

A subset of jumbo phages have recently been shown to encode a 'phage nucleus' for sequestering the phage genome away from host nucleolytic attack. Eliza Nieweglowska (University of California, San Francisco) and colleagues published a new p

In a new paper in Cell Reports, Beatriz Beamud (Universidad Complutense de Madrid) and colleagues report on their study of the genetic determinants of host tropism in Klebsiella phages. They isolated 46 phages to challenge 138 representativ

Live-cell fluorescence microscopy shows that mycobacteriophage infection of Mycobacterium smegmatis depends on the host nucleoid-associated protein Lsr2, which reorganizes away from host replication foci to set up zones of phage DNA replica

Save the date! The Evergreen International Phage Meeting is back this year (and back on campus)! Confirmed dates: Aug 6-11th 2023. 500 people max. Details to come!

The 28th Biennial Conference on Phage/Virus Assembly will be held at Shrigley Hall in Macclesfield, UK from 18-23 June 2023.

On Feb 28 at 5 PM East Africa Time, the Africa Phage Forum will be hosting a talk by Dr. Evelien Adriaenssens (Quadram Institute; Chair of ICTV Bacterial Viruses Committee) on the recently announced changes to phage taxonomy, including the 

In this new paper in Virus Evolution, Eric Olo Ndela (Université Clermont Auvergne, France) and colleagues report the discovery of sixteen complete microvirus genomes that represent two novel groups of microviruses, tentatively named Reekee

In a new paper in Cell, Brianna Duncan-Lowey (Harvard Medical School) and colleagues determined the cryo-EM structures of the RADAR defense complex, revealing RdrA as a heptameric, two-layered AAA+ ATPase and RdrB as a dodecameric, hollow c

A new paper by Pablo Quirós (Universitat de Barcelona) and colleagues published in The ISME Journal reports the isolation of the first phage infecting some Nitrosomonas species. This polyvalent virulent phage (named ΦNF-1) infected Nitrosom

Soo Khim Chan (University of California San Diego) and colleagues have developed peptides which bind specifically to Pseudomonas phage Good Vibes, which may enable real-time analysis of phage in vivo and monitor the efficacy of phage therap

In a new paper in Biotechnology Advances, Wajid Hussain (Huazhong University of Science and Technology) and colleagues review genetic engineering approaches for bacteriophages, with a focus on their potential applications.

On Feb 28 at 5PM East Africa Time, Phage Kenya Consortium will be hosting a talk by Dr. Evelien Adriaenssens (Quadram Institute; Chair of ICTV Bacterial Viruses Committee) on the recently announced changes to phage taxonomy, including the a

On February 8 at 9:30am GMT the UK Parliament Science and Technology Committee will be holding a public oral evidence session for "The antimicrobial potential of bacteriophages."

The MDPI Journal 'Cells' is hosting a special issue entitled Phage Therapy and Phage-Derived Enzymes as Antibacterial Agents led by Guest Editors Drs. Stephen Abedon, Katarzyna Danis-Wlodarczyk, Razi Kebriaei, and Aleksandra Petrovic Fabija

Researchers from UC San Diego, the J. Craig Venter Institute and Yale University have been awarded $10 million by the Howard Hughes Medical Institute (HHMI) to support research on using jumbo viruses as new therapeutic agents.

In this new paper in Frontiers in Microbiology, Qin Qi (Macquarie University, Australia) and colleagues present evidence that temperate and virulent (lytic) bacteriophages (phages) carry integrons. Integrons are mobile genetic elements that

In a new paper in PNAS, Benoit Pons (University of Exeter) and colleagues show that antibiotics that target the protein translation machinery can alter the outcome of bacteria-phage interactions by interfering with the production of phage-e

A new paper by Jan Finke (Hakai Institute, Canada) and colleagues describes Deep6, a deep learning model for classification of metatranscriptomic sequences into prokaryotes, eukaryotes, or one of the four viral realms (Duplodnaviria, Varidn