Search

Yunha Hwang and colleagues found that virus-host interactions in dense hydrothermal mats involve crossing microbial domains and nested metabolisms. They saw that unrelated microbes encode CRISPR immunity against the same viruses, suggesting

Nikhil George & Laura Hug examined a landfill via virus-host CRISPR spacer mapping, and found multiple examples of atypical virus-host dynamics, such as hyper-targeted viral populations, interviral conflicts, and non-specific viruses.

Tram Le and colleagues show the therapeutic potential of IV phage for recurrent urinary tract infections, describing a kidney transplant recipient with ESBL Klebsiella pneumoniae who was successfully treated with 4 weeks of IV phage therapy

Olaya Rendueles and colleagues have described how fitness costs drive competition between lysogenic and sensitive bacteria by co-cultivating a phage-sensitive strain and a polylysogenic Klebsiella pneumoniae strain under different phage pre

Top Agar Question This is a basic question but one I do need advice with. My high school phage team will begin looking for a phage next fall from a new host. The host has not been studied much for phages. How do you choose a top agar for n

Phages seem to be saving lives left and right, but still, they remain unapproved drugs in most countries. Pharma companies don't sell them; hospitals and pharmacies don’t stock them. In this Wired article, Maryn McKenna covers phage therapy

In a new paper in Nature, Joseph Kreitz (Howard Hughes Medical Institute) and colleagues show that Photorhabdus virulence cassette (PVCs), part of a class of syringe-like nanomachines resembling phage tails, can be reprogrammed for protein

By analyzing metagenomic samples from IBD patients, Shaqed Carasso (Technion-Israel Institute of Technology) and colleagues identified invertible regions that correlate with disease, including Bacteroides fragilis polysaccharide-A, which is

This week's EMDB (Electron Microscopy Data Bank) release includes this beautiful 4.4 Å single particle CryoEM structure of a phicrAss001 virion!

This review by Fazal Mehmood Khan (Shenzhen University) and colleagues provides an update on the use of animal models in phage therapy, summarizing preclinical approaches in various in-vivo models and highlighting the need for pharmacokinet

Hello Phage People, Does anyone use Phage DNA Isolation Kit from Norgen Biotek? I'm using this kit and trying to increase the DNA concentration. I already did all the additional steps but does anyone have any tricks for increasing concentra

The recording of the recent Clubhouse audio conversation on GMP phage therapy production (’Just say no to GMP?’) has just been posted! This was a talk hosted last week by Sabrina Green, Adriana Hernandez, Jean-Paul Pirnay, Patrick Druggan,

The UK parliament recently heard evidence on phages for AMR. According to Stephanie Lesage via LinkedIn: “There was a general consensus on the need to embrace the biological and unique nature of phages and find more suitable approaches to s

Viruses of Microbes is happening this year in Tbilisi, Georgia July 3rd-7th. The deadline for abstract submission is May 1st.

The Canadian Society of Microbiologists conference (CSM) is hosting a phage session (Bacteriophage and bacterial defense systems). This year, the conference is hosted in Halifax from June 25th-28th, and the abstract deadline is April 17th.

The International Workshop on Ecophage is happening in Valencia, Spain from Sept 12-13, 2023. Join experts in phage research, farmers, food companies, policy makers, and consumer reps in a workshop on phage-based strategies for preventing A

Phage Phriday is back talking GMP & phages w/regulators & experts in the field. “Just say no to GMP?” with @Motherofphage, @AdriCaroHM, @PaulPirnay, Barbara Brenner @phages2patients, Patrick Druggan, and more! Friday, 31 Mar at 8:00 PM CEST

The 4th International Conference on #Bacteriophage Research and #AntimicrobialResistance is happening at the University of Madras, Guindy Campus, Chennai, India September 28-30, 2023.

In this CIDRAP podcast episode, 'Phage Against the Routine', Steffanie Strathdee, Greg Merril, Patrick McGann, and Jason Bennett discuss how infections caused by resistant Acinetobacter impact patients and new treatments.

Akos Nyerges (Harvard Medical School) and colleagues published a new paper on developing a genetic firewall to prevent viral infections and gene transfer in organisms, which could be used to make any organism resistant to all natural viruse