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  1. UpdatesSep 22, 2023

    Benjamin Adler and colleagues have developed a broad-spectrum phage functional genomics platform using programmable RNA-bindi

    Benjamin Adler and colleagues have developed a broad-spectrum phage functional genomics platform using programmable RNA-binding protein dRfxCas13d, uncovering hidden infection strategies and predicting over 90 essential genes in phage genom

    UpdatesCRISPRi-ARTPhage engineeringPreprint
  2. UpdatesSep 22, 2023

    Jingxian Yang and colleagues have discovered that agr (quorum sensing) induction reduces expression of tarM (which encodes a

    Jingxian Yang and colleagues have discovered that agr (quorum sensing) induction reduces expression of tarM (which encodes a glycosyltransferase responsible for modification of the major S. aureus phage receptor). This allows lytic phage St

    UpdatesResearch paperPhage susceptibilityQuorum sensing
  3. UpdatesSep 22, 2023

    Phables, a new computational method developed by Vijini Mallawaarachchi and colleagues, resolves phage genomes from fragmente

    Phables, a new computational method developed by Vijini Mallawaarachchi and colleagues, resolves phage genomes from fragmented viral metagenome assemblies, enabling the recovery of over 49% more high-quality phage genomes compared to existi

    UpdatesBioinformatics toolComparative GenomicsViral Identification
  4. UpdatesSep 20, 2023

    Halomonas phage vB_HmeY_H4907 from the Mariana Trench is the deepest isolated siphovirus

    Researchers led from the Ocean University of China characterised Halomonas phage vB_HmeY_H4907, isolated from surface sediment of the Mariana Trench at a depth of 8,900 m. The authors describe it as the deepest isolated siphovirus from the

    UpdatesPapersPhage Biology
  5. UpdatesSep 20, 2023

    Virus-based pyroelectricity: engineered M13 phage generates an electrical potential from heat

    University of California, Berkeley researchers report the first observation of heat-induced electrical potential generation on a virus, studying the pyroelectric properties of the M13 phage. Modifying the pVIII coat protein with different n

    UpdatesPapersPhage Engineering
  6. UpdatesSep 15, 2023

    Did you know that VoM is heading down under? The Viruses of Microbes (VoM) Conference will take place in Cairns, Queensland,

    Did you know that VoM is heading down under? The Viruses of Microbes (VoM) Conference will take place in Cairns, Queensland, Australia, July 15-19th, 2024. Registration is open now!

    UpdatesCommunityViruses of MicrobesISVMConference
  7. UpdatesSep 15, 2023

    Katelyn McNair, the creator of Phanotate, has introduced a new tool called Genotate, designed to identify and predict coding

    Katelyn McNair, the creator of Phanotate, has introduced a new tool called Genotate, designed to identify and predict coding genes in phage genomes. Now in final stages of development, it’s built to take your phage genome annotation and an

    UpdatesCommunityBioinformatics toolPhage GenomicsGenome Annotation
  8. UpdatesSep 15, 2023

    Intralytix has announced the launch of a Phase 1/2a clinical trial of its VRELysin™ phage preparation to assess safety and ef

    Intralytix has announced the launch of a Phase 1/2a clinical trial of its VRELysin™ phage preparation to assess safety and efficacy in healthy and VRE-colonized subjects at UPMC in Pittsburgh, Pennsylvania.

    UpdatesPhage therapyClinical TrialBiotech news
  9. UpdatesSep 15, 2023

    A new Canadian phage CRO, Qeen Bio is offering a variety of services including phage characterization, cell banking, fermenta

    A new Canadian phage CRO, Qeen Bio is offering a variety of services including phage characterization, cell banking, fermentation, downstream processing, formulation, lab services for phage clinical trials, and regulatory consulting for pha

    UpdatesPhage CharacterizationFormulation ServicesBiotech news
  10. UpdatesSep 15, 2023

    Erin Attrill (University of Exeter) and colleagues found that slow-growing E. coli cells survive phage T4 in isolation, but f

    Erin Attrill (University of Exeter) and colleagues found that slow-growing E. coli cells survive phage T4 in isolation, but fast-growing cells survive when surrounded by their clonal kin cells.

    UpdatesResearch paperPhage-host interactions
  11. UpdatesSep 15, 2023

    Pedro Leao (University of Texas, Austin) and colleagues have determined that the Asgardarchaeota, a group of archaea related

    Pedro Leao (University of Texas, Austin) and colleagues have determined that the Asgardarchaeota, a group of archaea related to eukaryotes, played important roles in the evolution of viral protection in eukaryotes.

    UpdatesArchaeaEukaryotesDefense Systems
  12. UpdatesSep 15, 2023

    Justin Leavitt (University of Utah) and colleagues report that the P22-encoded SieA protein is the only phage protein require

    Justin Leavitt (University of Utah) and colleagues report that the P22-encoded SieA protein is the only phage protein required for exclusion by the SieA system, blocking DNA injection by P22 and its relatives, but having no effect on infect

    UpdatesBacteriophageExclusionPreprint
  13. UpdatesSep 13, 2023

    Pediococcus inopinatus with a well-developed CRISPR-Cas system dominates long-term fermented kimchi

    Researchers at the World Institute of Kimchi found that Pediococcus inopinatus is generally dominant in Mukeunji, long-term fermented kimchi in the final stage of fermentation. Its genome has a well-developed CRISPR system with an extra cop

    UpdatesPapersMicrobiome
  14. UpdatesSep 8, 2023

    Medical-grade phage is now available for expanded access through Tolka.ai's waitlist, after a year of hard work by Johan Wiks

    Medical-grade phage is now available for expanded access through Tolka.ai's waitlist, after a year of hard work by Johan Wikstrom, Keqing Li, Thomas Hunt, Volodymyr Kulchytskyi, and the broader phage community; phage researchers can learn m

    UpdatesCommunityMedical-grade PhageInvestigational TreatmentExpanded Access
  15. UpdatesSep 8, 2023

    Interested in graduate microbiome research at Penn State University? Register today for @PSUmBiome Graduate Studies Open Hous

    Interested in graduate microbiome research at Penn State University? Register today for @PSUmBiome Graduate Studies Open House Oct 12th, 6-7 PM ET.

    UpdatesCommunityWebinarMicrobiomeGrad studies
  16. UpdatesSep 8, 2023

    Congrats to Vivek Mutalik and colleagues, who have received funding from the BRaVE initiative (US Dept of Energy) to expand t

    Congrats to Vivek Mutalik and colleagues, who have received funding from the BRaVE initiative (US Dept of Energy) to expand their Phage Foundry, a platform for phage countermeasures against AMR pathogens.

    UpdatesFunding newsphage therapy
  17. UpdatesSep 8, 2023

    Cytophage Technologies has announced a distribution agreement with a leading animal health company in South Asia. The initial

    Cytophage Technologies has announced a distribution agreement with a leading animal health company in South Asia. The initial product for distribution will be Cytophage’s FARMPHAGE (TM) formulation for the poultry industry.

    UpdatesBiotech news
  18. UpdatesSep 8, 2023

    Eray Enustun (UCSD) and colleagues have used proximity labeling and localization mapping to systematically map out the protei

    Eray Enustun (UCSD) and colleagues have used proximity labeling and localization mapping to systematically map out the protein interaction network of the ‘phage nucleus’ made by jumbo phages.

    UpdatesResearch paperProximity labelingJumbo phagesPhage nucleus
  19. UpdatesSep 8, 2023

    Jens Hör (Weizmann Institute of Science) and colleagues have discovered that bacteria conjugate ubiquitin-like proteins to in

    Jens Hör (Weizmann Institute of Science) and colleagues have discovered that bacteria conjugate ubiquitin-like proteins to interfere with phage assembly.

    UpdatesPreprintPhage-host interactionsPhage assembly
  20. UpdatesSep 8, 2023

    Phage researcher Pranav Johri discusses phage therapy and antimicrobial resistance in India in a recent article in The Microb

    Phage researcher Pranav Johri discusses phage therapy and antimicrobial resistance in India in a recent article in The Microbiologist

    UpdatesResearch paper
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