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Ep 18: Discussion of Phage Therapy for CF Patients - Rebekah Dedrick

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    Issue 323Jessica Sacher

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231 news items

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  • Phage prohead proteases activate CBASS antiphage immunity (Science)

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  1. UpdatesJun 25, 2019

    Seeking phage research opportunity

    Mahsa Yazdi Gorgan, Iran I recently graduated with a Ph.D. in Microbiology from the University of Isfahan, Iran. My thesis was entitled “Isolation and characterization of lytic bacteriophages against some of the most common bacterial causes

    UpdatesCommunitySeeking opportunityPost DocResearch
  2. UpdatesJun 25, 2019

    Seeking phage research opportunity

    Mahsa Yazdi Gorgan, Iran I recently graduated with a Ph.D. in Microbiology from the University of Isfahan, Iran. My thesis was entitled “Isolation and characterization of lytic bacteriophages against some of the most common bacterial causes

    UpdatesCommunitySeeking opportunityPost DocResearch
  3. UpdatesJun 22, 2019

    A 13-month old infant was successfully treated with phage therapy (English article | Dutch article) post-liver transplant at

    A 13-month old infant was successfully treated with phage therapy (English article | Dutch article) post-liver transplant at the Saint-Luc University Hospital in Brussels. Phages were obtained from the Queen Astrid Military Hospital—read mo

    UpdatesPhage TherapyQueen Astrid Military HospitalMagistral PhageNews
  4. UpdatesJun 22, 2019

    The BBC's CrowdScience has done a fantastic podcast interview on phage therapy and phage hunting (31 min), where they travel

    The BBC's CrowdScience has done a fantastic podcast interview on phage therapy and phage hunting (31 min), where they travel to Tbilisi, Georgia, visit the Eliava Phage Therapy Center, and go phage-hunting with the scientists there. They ev

    UpdatesPodcastEliava Institute
  5. UpdatesJun 22, 2019

    The Cystic Fibrosis Foundation, a world-leading non-profit that drives CF research and development, has teamed up with CARB-X

    The Cystic Fibrosis Foundation, a world-leading non-profit that drives CF research and development, has teamed up with CARB-X, a global partnership investing in antibacterial innovation, in pursuit of a new Infection Research Initiative. Th

    UpdatesWebinarFundingCystic Fibrosis
  6. UpdatesJun 22, 2019

    The Society for Bacteriophage Research and Therapy, SBRT, a new society in Varanasi, India, is accepting new members. Their g

    The Society for Bacteriophage Research and Therapy, SBRT, a new society in Varanasi, India, is accepting new members. Their goal is to work together as a team for the betterment of bacteriophages and their positive global impact. Find them

    UpdatesPhage Society
  7. UpdatesJun 22, 2019

    A new phage pharmacokinetics paper by Katarzyna Hodyra-Stefaniak and colleagues in Krystyna Dabrowska's group at the Polish A

    A new phage pharmacokinetics paper by Katarzyna Hodyra-Stefaniak and colleagues in Krystyna Dabrowska's group at the Polish Academy of Sciences has demonstrated a "short-circulating phage" phenotype that has implications for engineered phag

    UpdatesPhage PharmacokineticsResearch
  8. UpdatesJun 22, 2019

    A new patent on phage compositions and uses was published this month by Paul Turner, Benjamin Chan and John Wertz. Their inve

    A new patent on phage compositions and uses was published this month by Paul Turner, Benjamin Chan and John Wertz. Their invention includes phage compositions and methods to increase antibiotic sensitivity in bacteria, a pharmaceutical comp

    UpdatesPhage Patent
  9. UpdatesJun 22, 2019

    Diane Shader Smith is the mother of Mallory Smith, the 25-year-old who passed away in 2017 from an antibiotic resistant lung

    Diane Shader Smith is the mother of Mallory Smith, the 25-year-old who passed away in 2017 from an antibiotic resistant lung infection. Diane has given a TEDx talk (14 min) about Mallory's life, legacy and memoir: Salt in My Soul. Diane des

    UpdatesTedx TalkVideo
  10. UpdatesJun 22, 2019

    This week on #PhageTwitter: a fantastic and informative Twitter thread (with images and videos!) by Patrick R. Secor (@PRSeco

    This week on #PhageTwitter: a fantastic and informative Twitter thread (with images and videos!) by Patrick R. Secor (@PRSecor) on how filamentous P. aeruginosa phage Pf spontaneously forms liquid crystals in the presence of polymers, which

    Updates#BestOfPhageTwitter
  11. UpdatesJun 22, 2019

    Two new phage bioinformatics tools for you this week: first, a phage host finding tool: link phages and potential hosts by fi

    Two new phage bioinformatics tools for you this week: first, a phage host finding tool: link phages and potential hosts by finding shared attachment sites for prophage integration (GitHub), and second, Prophage Hunter: an integrative huntin

    UpdatesBioinformatics Tool
  12. UpdatesJun 22, 2019

    This NPR article discusses Locus Biosciences' upcoming E. coli urinary tract infection phage therapy trial and interviews one

    This NPR article discusses Locus Biosciences' upcoming E. coli urinary tract infection phage therapy trial and interviews one of the trial volunteers—Alfonso Evans, a US Army veteran who was paralyzed by a spinal cord injury and thus suffer

    UpdatesPhage TherapyUTIClinical Trials
  13. UpdatesJun 22, 2019

    Rick Bright, Director of BARDA, shared his opinion on how the recent bankruptcy of Achaogen (a BARDA-funded biotech that rece

    Rick Bright, Director of BARDA, shared his opinion on how the recent bankruptcy of Achaogen (a BARDA-funded biotech that recently brought an antibiotic to market, then saw such poor sales that it closed its doors) proves that the marketing

    UpdatesBARDAAntimicrobial Development
  14. UpdatesJun 22, 2019

    A new paper by Alexander Meeske and colleagues at Rockefeller University shows that CRISPR-Cas13, poorly understood compared

    A new paper by Alexander Meeske and colleagues at Rockefeller University shows that CRISPR-Cas13, poorly understood compared to other CRISPR-Cas systems, leads to host cell growth inhibition (through degradation of both phage and host RNA)

    UpdatesResearchCRISPR
  15. UpdatesJun 22, 2019

    An interesting reflection by Prof. Marc Bonten of UMC Utrecht on the current impasse in the Netherlands when it comes to the

    An interesting reflection by Prof. Marc Bonten of UMC Utrecht on the current impasse in the Netherlands when it comes to the need for phage clinical trials, and on UMCU's recent discussions with national health authorities on the matter.

    UpdatesOpinionClinical TrialsPhage Therapy
  16. UpdatesJun 22, 2019

    A new paper by Bryan Hsu and colleagues at Harvard and Brigham and Women's Hospital showed (in the mouse gut) that introducin

    A new paper by Bryan Hsu and colleagues at Harvard and Brigham and Women's Hospital showed (in the mouse gut) that introducing phages led to predictable shifts in the targeted population, but also had "cascading effects" on non-phage-suscep

    UpdatesResearchMicrobiomeMetabolome
  17. UpdatesJun 22, 2019

    Virome datasets are being generated at unprecedented rates, but new data are rarely cross-compared, which leads to virus nove

    Virome datasets are being generated at unprecedented rates, but new data are rarely cross-compared, which leads to virus novelty being inflated in new datasets and many viral sequences going undetected. A new preprint by Ann Gregory and col

    UpdatesViromePreprintDatabase
  18. UpdatesJun 22, 2019

    BiomX, a phage therapy biotech company, just announced that it's licensed new bacterial targets for commercialization of phag

    BiomX, a phage therapy biotech company, just announced that it's licensed new bacterial targets for commercialization of phage therapies for Primary Sclerosing Cholangitis (PSC; a rare, progressive liver disease). The targets: strains of Kl

    UpdatesBiotechPhage TherapyMicrobiome
  19. UpdatesJun 22, 2019

    The now-constant flood of phage sequence data is showing that tailed phages are more genetically diverse than previously thou

    The now-constant flood of phage sequence data is showing that tailed phages are more genetically diverse than previously thought. This has led to a re-classification of tailed phages, which is described in a new paper by Jakub Barylski and

    UpdatesPhage classificationTaxonomyResearch
  20. UpdatesJun 22, 2019

    #### Dear phage community, We recognize the importance of supporting fundamental phage research, because effective phage the

    #### Dear phage community, We recognize the importance of supporting fundamental phage research, because effective phage therapy starts from a basic understanding of phages. We're excited to announce that we're working on publishing affo

    UpdatesPhage DirectoryAnnouncement
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