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Retrons are bacterial genetic elements comprised of a reverse transcriptase (RT) and a non-coding RNA, but their functions have been unknown for decades. Adi Millman (Weizmann Institute of Science, Israel) and colleagues published a new pre

Bacterial pathogens of fish cause major problems for fish farmers. Bernardo Veyrand‐Quirós (Instituto Politécnico Nacional, Mexico) and colleagues published a new paper in the Journal of Applied Microbiology showing that phage therapy incre

Another story about phage application in marine aquaculture! Hyoun Joong Kim (Seoul National University) and colleagues published a new paper in Microorganisms showing the preventive effects of phage against pathogenic Vibrio coralliilyticu

Ayesha Hassim (University of Pretoria, South Africa) and colleagues published a new paper in Microorganisms showing that an "aggressively lytic" phage hampered isolation of Bacillus anthracis from samples collected from the carcass of a wil

Lucy Furfaro (University of Western Australia) and colleagues published a new paper in PLOS ONE showing host range, morphological and genomic characterization of phages with activity against clinical Streptococcus agalactiae isolates from p

Paul Hyman, Ashland University Are you modifying phages, genetically or chemically, to improve their ability to act as therapeutics? Attaching toxins so the phage capsid provides specificity to target bacteria? Creating phage based vaccines

Emmanuel Nnadi, Plateau State University We have in our collection, E. coli, P. aeruginosa and S. aureus phages. We would wish to characterize them molecularly and under the microscope. We do not have any such capacity in our lab. We see fo

I'm looking for a collaborator on #phage #phagetherapy #Acinetobacter & antimicrobial resistance. The call is specifically for a collaboration with Japan. Please let me know if you know anyone - Thank you! DM or email: Leptihn(at)intl.zju.e

Hello, #phage tweeps! I have a question. Suppose you have a bunch of phage MAGs, each composed of more than 1 contig: how do you calculate their completeness? I have a couple of ideas, but I still need to evaluate their feasibility. - @Mich

Phage Directory Do you have a new or upcoming paper that you're excited about sharing with the phage community? We'd like to publish more Behind the Paper articles (like last week's by Prof. Yves Briers) in future Capsid & Tail issues. To t

Armata Pharmaceuticals just received a $15 million award from the US Department of Defense to take its Staphylococcus aureus phage cocktail to phase 1b/2 clinical trials.

How should we optimally design phage cocktail timing and dosage to deal with evolutionary escape of pathogens? Guanlin Li and Chung Yin Leung (Georgia Institute of Technology) and colleagues published a new paper on using mathematical model

Thilini Jayasinghe (University of Auckland, New Zealand) and colleagues published a new paper in Frontiers in Cellular and Infection Microbiology showing differences in compositions of gut bacterial populations and phages in 5–11 year-olds

Katarzyna Leskinen (University of Helsinki) and colleagues published a new paper in Viruses on how they determined the genome of a non-sequenceable Yersinia phage YerA41 via RNA-sequencing.

Gang Wang (Jiangnan University) and colleagues published a new paper in Frontiers in Microbiology showing the diversity of the CRISPR-Cas system and prophages present in the genome reveals co-evolution of Bifidobacterium pseudocatenulatum a

What's new in the world of molecular mechanisms of lysogeny? Margit Pedersen and colleagues (University of Copenhagen and Technical University of Denmark) have published a new paper in Scientific Reports investigating repressor binding inte

Intralytix is a phage company in Maryland, USA that began in 1998 developing phage products for food; recently they've moved toward human therapy. Read about their recent progress here, including their new NIAID-funded Shigella phage clinic

A 2020 paper in PHAGE evaluates methods for processing sputum from patients with cystic fibrosis to detect Pf bacteriophage virion-derived nucleic acid, testing the effect of bead beating, DNase digestion and heating steps and quantifying P

Phage Directory We're excited to announce that we've launched an ongoing sponsorship program for Phage Directory's community building activities, and we have our first Bronze Sponsor: JAFRAL! JAFRAL is the world's only CMO/CRO dedicated pr

Phage Directory Phage Directory's Virtual Event Series, PHAVES, starts this Tuesday, June 16 at 9:00 AM MDT (GMT-6)! For the kickoff event, Jessica and Jan will introduce the virtual series and Phage Directory's projects for 2020, and we'll