Community post

Garyk Brixi (Arc Institute and Stanford University) and colleagues have expanded on Evo 1, which was trained on prokaryotic and phage genomes, to create Evo 2, now the largest AI model in biology. It was trained on 9.3 trillion nucleotides from 128,000 genomes across all domains of life (spanning bacteria, archaea, phages, humans, plants, and other single-celled and multi-cellular species). It identifies genetic patterns, predicts mutation effects, and designs genome-scale sequences. Evo 2 is fully open-source — play with it here!