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Structural investigation of QatB and QatC proteins in QatABCD anti-phage defense

A structural and functional study of QatB and QatC, two components of the four-protein QatABCD anti-phage defense system. QatC bound to the ATP analog AMPPNP and the QatB-QatC heterodimer were solved, and structural analysis suggests QatB may serve as a substrate of QatC, implicating a potential regulatory mechanism.

SourceNature Communications — doi:10.1038/s41467-026-73101-4