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Jolien Onsea and colleagues from KU Leuven, University Hospitals Leuven, and the Queen Astrid Military Hospital in Belgium successfully used phage therapy to treat four patients with severe musculoskeletal infections. Importantly, the authors developed a standardized treatment protocol for use of phages to treat similar infections. This includes assembling a "multidisciplinary phage task force" consisting of infectious disease specialists, pharmacists, microbiologists, surgeons, and phage scientists, and documenting all results in a database to inform future studies.