Genomic characterization of four Salmonella-specific bacteriophages and evaluation of their cocktail efficacy in milk (Food Science and Biotechnology)

Jung and colleagues analysed the genomic, proteomic and functional characteristics of four bacteriophages (STP-1 to STP-4) targeting Salmonella Typhimurium, finding lysis-related genes (holin, endolysin, RZ-like spanins) and no genes linked to human toxicity or antibiotic resistance. A cocktail applied to milk at MOI 1,000 reduced bacterial counts by 2.11 log CFU/mL after 7 days, more than the same cocktails achieved on chicken breast in a previous study.