Opportunities

ENABLE-2 offers antibiotic hit-to-lead development support

Review cutoff12 March 2027
EligibilityResearchers at publicly funded universities and research institutes in Europe, including UK, Norway and Switzerland; compounds must meet the published activity, development and IP thresholds.
FundingFree development advice and platform access; funding for approved assays unavailable within the platform.

ENABLE-2 accepts expressions of interest from researchers at publicly funded universities and research institutes across Europe, including the UK, Norway and Switzerland. Its Hit-to-Lead programme provides expert advice, experimental platforms and funding for approved external assays, while applicants retain data and IP rights. It focuses on direct-acting antibiotic small molecules and eligible natural products against priority resistant bacteria. Applications are continuously open; March 12, 2027 is the cutoff for consideration at the April portfolio review. Begin with a non-confidential expression of interest.

ApplyApplication details