checkV tool for metagenomes

Metagenomics is enabling discovery of millions of new viral sequences, but no tools previously existed to estimate their quality. Stephen Nayfach (DOE Joint Genome Institute) and colleagues created CheckV, an automated pipeline for assessing the quality of metagenome-assembled viral genomes. They validated the tool on public datasets and found that just 3.6% of viral sequences are high-quality or complete. Preprint | Tool.