50—prophage manip of respiration

Jeffrey Carey (University of Pennsylvania) and colleagues have shown that a temperate E. coli phage reprograms its host's regulation of an anaerobic respiratory system. They found that the prophage disables the bet-hedging strategy that aids its host during rapid oxygen depletion. Plus, the phage achieved this by an as-yet undescribed mechanism, where the phage replaces a host promoter with its own promoter.